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Full-Text Articles in Life Sciences
Ab Blood Type And Its Genetic Relationship To Alzheimer’S Disease, Mark Wadsworth, John S. K. Kauwe
Ab Blood Type And Its Genetic Relationship To Alzheimer’S Disease, Mark Wadsworth, John S. K. Kauwe
Journal of Undergraduate Research
Alzheimer’s Disease (AD) is a debilitating disease that has increased the hardship of many lives. Many people above the age of 65 have been diagnosed with this genetically complex disease, which financially and emotionally burdens those diagnosed and their families. Earlier this year a study was released that found, using a dataset of individuals that have had strokes, that individuals with AB blood type are more at risk of developing cognitive impairment[1]. This study however was not looking at the genetics of AD. My objective in performing this study was to see if there is a genetic association between Alzheimer’s …
Analysis Of Hmgcr As A Genetic Modifier For Alzheimer’S Disease, Brian Davis, Dr. John S. K. Kauwe
Analysis Of Hmgcr As A Genetic Modifier For Alzheimer’S Disease, Brian Davis, Dr. John S. K. Kauwe
Journal of Undergraduate Research
Alzheimer’s disease (AD) is a chronic neurodegenerative disorder that occurs predominantly later in life and represents the fourth most common cause of death in the developed world. Given the absence of curative treatment, discovering the factors related to the development of AD and the conversion from mild cognitive impairment (MCI) to AD is one of the most urgent medical mysteries affecting the aging population. The search for the identification of genes contributing to AD led to the identification of 695 candidate genes of which a surprising number are directly involved in lipid metabolism at the level of transport, synthesis, storage, …
Association Of Rare Genetics Variants To The Protection Of Alzheimer’S Disease In The Cache County Data Set, Josue David Gonzalez Murcia, John Kauwe
Association Of Rare Genetics Variants To The Protection Of Alzheimer’S Disease In The Cache County Data Set, Josue David Gonzalez Murcia, John Kauwe
Journal of Undergraduate Research
Alzheimer’s disease is one of the top 10 causes of death in the world and the 6th leading cause of death in the United States, with 5.5 million people diagnosed with the disease. Alzheimer’s cannot be cured, prevented or slowed. Most research with Alzheimer’s disease has been done on SNPs that have a relatively high frequency in the population this has helped facilitate researchers in finding a broad genetic pathway in the development of Alzheimer’s disease (Naj et al. 2011; Harold et al. 2009). Our research will focus on a very rare SNP, with a much lower frequency than previously …