Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 4 of 4

Full-Text Articles in Life Sciences

Anti-Quorum Sensing Agents From South Florida Medicinal Plants And Their Attenuation Of Pseudomonas Aeruginosa Pathogenicity, Allison L. Adonizio Mar 2008

Anti-Quorum Sensing Agents From South Florida Medicinal Plants And Their Attenuation Of Pseudomonas Aeruginosa Pathogenicity, Allison L. Adonizio

FIU Electronic Theses and Dissertations

With the difficulty in treating recalcitrant infections and the growing resistance to antibiotics, new therapeutic modalities are becoming increasingly necessary. The interruption of bacterial quorum sensing (QS), or cell-cell communication is known to attenuate virulence, while limiting selective pressure toward resistance. This study initiates an ethnobotanically-directed search for QS inhibiting agents in south Florida medicinal plants. Fifty plants were screened for anti-QS activity using two biomonitor strains, Chromobacterium violaceum and Agrobacterium tumefaciens. Of these plants, six showed QS inhibition: Conocarpus erectus L. (Combretaceae), Chamaecyce hypericifolia (L.) Millsp. (Euphorbiaceae), Callistemon viminalis (Sol.ex Gaertn.) G. Don (Myrtaceae), Bucida burceras L. (Combretaceae), Tetrazygia …


Antibacterial Activities Of Aqueous And Alcoholic Extracts Of 34 Indian Medicinal Plants Against Some Staphylococcus Species, Jigna Parekh, Sumitra Chanda Jan 2008

Antibacterial Activities Of Aqueous And Alcoholic Extracts Of 34 Indian Medicinal Plants Against Some Staphylococcus Species, Jigna Parekh, Sumitra Chanda

Turkish Journal of Biology

Thirty-four Indian medicinal plants belonging to 28 different families were screened for potential antibacterial activity against 3 Staphylococcus species, namely Staphylococcus aureus, Staphylococcus epidermidis, and Staphylococcus subflava. Antibacterial activity of aqueous and alcoholic extracts was performed by agar disc diffusion method and agar well diffusion method. The alcoholic extracts were more active than aqueous extracts for all the plants studied. The most susceptible bacterium was S. aureus. The methanol extract of Woodfordia fruticosa showed the best antibacterial activity. The in vitro susceptibility testing of the studied staphylococcus strains was done against standard antibiotics.


The Antioxidant Activity Of Some Medicinal Plants, Prateek Kumar Jain, Veerasamy Ravichandran, Simant Sharma, Ram. K. Agrawal Jan 2008

The Antioxidant Activity Of Some Medicinal Plants, Prateek Kumar Jain, Veerasamy Ravichandran, Simant Sharma, Ram. K. Agrawal

Turkish Journal of Biology

The antioxidant properties of the methanol extracts of 10 medicinal plants were evaluated with the DPPH (1,1-diphenyl-2-picryl hydrazyl) test, hydroxyl scavenging test, and lipid peroxidation assay. The methanol extract of Emblica officinalis was the most active according to the DPPH test, with an IC_{50} value of 7.92 ± 0.1 \mug/ml, followed by Asparagus racemosus, with an IC_{50} value of 9.28 ± 0.2 \mug/ml. The minimum free radical scavenging activity was shown by Zingiber officinale, with an IC_{50} value of 44.48 ± 1.8 \mug/ml. The hydroxyl radical scavenging activity of the methanolic extracts of various plants was as follows: Asparagus racemosus …


In Vitro Antimicrobial Activity Of Salvadora Persica L. Extracts Against Some Isolated Oral Pathogens In Iraq, Firas A. Al-Bayati, Khudir D. Sulaiman Jan 2008

In Vitro Antimicrobial Activity Of Salvadora Persica L. Extracts Against Some Isolated Oral Pathogens In Iraq, Firas A. Al-Bayati, Khudir D. Sulaiman

Turkish Journal of Biology

Aqueous and methanol extracts of Salvadora persica L., a plant used in Iraq for oral hygiene, was investigated for its antimicrobial activities against 7 isolated oral pathogens: Staphylococcus aureus, Streptococcus mutans, Streptococcus faecalis, Streptococcus pyogenis, Lactobacillus acidophilus, Pseudomonas aeruginosa, and Candida albicans using disc diffusion and micro-well dilution assays. According to both antimicrobial assays the aqueous extract inhibited all isolated microorganisms, especially the Streptococcus species, and was more efficient than the methanol extract, which was resisted by Lacto. acidophilus and Ps. aeruginosa. The strongest antibacterial activity was observed using the aqueous extract against Strep. faecalis (zone of inhibition: 22.3 mm; …