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- Library Impact Statements (8)
- Honors Program Theses and Projects (4)
- Open Educational Resources (3)
- Spring Showcase for Research and Creative Inquiry (3)
- Honors Theses (2)
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- Lifelines - Biology Department Newsletter (2)
- Arts & Sciences Faculty Publications (1)
- Bioelectrics Publications (1)
- Chemistry & Biochemistry Faculty Publications (1)
- Department of Biological Sciences Publications (1)
- Faculty Publications (1)
- Faculty Works: Biology, Chemistry, and Environmental Studies (1)
- Post-Grant Reports (1)
- Working Papers on Science in a Changing World (1)
Articles 1 - 30 of 30
Full-Text Articles in Life Sciences
Biology Of Sharks And Their Relatives Bio 422, Joanna Burkhardt
Biology Of Sharks And Their Relatives Bio 422, Joanna Burkhardt
Library Impact Statements
No abstract provided.
The Cancer Stem Cell Marker Gsk3b, A Gene Involved In Oxidative Stress, Modulates Chemoresistance In Ovarian Cancer, Noelle L. Cutter Ph.D., Julia Fiederlein, Brianna Mcnulty, Cassandra Greco, Kimberly Doyle
The Cancer Stem Cell Marker Gsk3b, A Gene Involved In Oxidative Stress, Modulates Chemoresistance In Ovarian Cancer, Noelle L. Cutter Ph.D., Julia Fiederlein, Brianna Mcnulty, Cassandra Greco, Kimberly Doyle
Faculty Works: Biology, Chemistry, and Environmental Studies
The leading cause of death from gynecologic malignancies is epithelial ovarian cancer. These tumors are comprised of a highly heterogeneous population of cells, of which only a small subset of stem-like cells possess the ability to regenerate tumors in vivo. These cancer stem cells (CSCs) represent a significant clinical challenge as they are resistant to conventional cancer therapies and play essential roles in metastasis and tumor relapse. While chemotherapy is the preferred treatment modality, chemoresistance severely limits treatment success. It has been hypothesized that cancer stem cells are at the root of this problem. Their ability to self-renew and proliferate …
Undergraduate Research Science: Principles And Practice Bio 200, Michael Cerbo
Undergraduate Research Science: Principles And Practice Bio 200, Michael Cerbo
Library Impact Statements
No abstract provided.
Titration Of A Newtown Creek Environmental Water Sample To Determine The Amount Of Chloride Ions [Chemistry], Kevin Mark
Titration Of A Newtown Creek Environmental Water Sample To Determine The Amount Of Chloride Ions [Chemistry], Kevin Mark
Open Educational Resources
Main Course Learning Objectives:
The General Chemistry 1 (SCC 201) course has multiple course learning objectives, which articulate key introductory chemistry concepts that all STEM students should possess. In particular, the Newtown Creek titration experiment aligns with SCC 201 learning objectives of:
- Demonstrate an appreciation of the role of chemistry in various aspects of life
- Perform basic laboratory skills such as the proper execution of titration techniques
- Describe and explain the fundamental chemistry concept of solution concentration
- Analyze and represent experimental data in tables and graphs, interpret experimental results and write laboratory reports
In the SCC 201 laboratory, students are …
Human Biology Oer, Bio 1100, Course Outline, Tatiana Voza
Human Biology Oer, Bio 1100, Course Outline, Tatiana Voza
Open Educational Resources
This course will include selected biological concepts, including the chemical basis of life, cell structure and division, a broad survey of the major systems of the human body with a special emphasis on human health disease, human evolution and ecology. This course should provide students who do not plan to continue in the sciences or pre-health programs with a working knowledge of life science that will be useful in making informed decisions on health and the environment
Lifelines Fall 2019, Southern Adventist University
Lifelines Fall 2019, Southern Adventist University
Lifelines - Biology Department Newsletter
No abstract provided.
Biology Of Human Health And Disease Bio 482g, Michael Cerbo
Biology Of Human Health And Disease Bio 482g, Michael Cerbo
Library Impact Statements
No abstract provided.
Biology Of Medicine Bio 481x, Michael Cerbo
Biology Of Medicine Bio 481x, Michael Cerbo
Library Impact Statements
No abstract provided.
Nature And Nurture: How Our Genes And Environments Shape Our Lives Bio 440g, Michael Cerbo
Nature And Nurture: How Our Genes And Environments Shape Our Lives Bio 440g, Michael Cerbo
Library Impact Statements
No abstract provided.
Electrostatically Localized Proton Bioenergetics: Better Understanding Membrane Potential, James Weifu Lee
Electrostatically Localized Proton Bioenergetics: Better Understanding Membrane Potential, James Weifu Lee
Chemistry & Biochemistry Faculty Publications
In Mitchell's chemiosmotic theory, membrane potential Δψ was given as the electric potential difference across the membrane. However, its physical origin for membrane potential Δψ was not well explained. Using the Lee proton electrostatic localization model with a newly formulated equation for protonic motive force (pmf) that takes electrostatically localized protons into account, membrane potential has now been better understood as the voltage difference contributed by the localized surface charge density ([H-+L] + nΣ i=1 [M(i+)L]) at the liquid-membrane interface as in an electrostatically localized protons/cations-membrane-anions capacitor. That is, the origin of membrane …
A Rapid Viability And Drug‑Susceptibility Assay Utilizing Mycobacteriophage As An Indicator Of Drug Susceptibilities Of Anti‑Tb Drugs Against Mycobacterium Smegmatis Mc2 155, Gillian Catherine Crowley, Jim O'Mahony, Aidan Coffey, Riona G. Sayers, Paul D. Cotter
A Rapid Viability And Drug‑Susceptibility Assay Utilizing Mycobacteriophage As An Indicator Of Drug Susceptibilities Of Anti‑Tb Drugs Against Mycobacterium Smegmatis Mc2 155, Gillian Catherine Crowley, Jim O'Mahony, Aidan Coffey, Riona G. Sayers, Paul D. Cotter
Department of Biological Sciences Publications
Background: A rapid in-house TM4 mycobacteriophage-based assay, to identify multidrug resistance against various anti-tuberculosis drugs, using the fast-growing Mycobacterium smegmatis mc2 155 in a microtiter plate format was evaluated, based on phage viability assays. Methods: A variety of parameters were optimized before the study including the minimum incubation time for the drugs, phage and M. smegmatis mc2 155 to be in contact. An increase in phage numbers over 2 h was indicative that M. smegmatis mc2 155 is resistant to the drugs under investigation, however when phage numbers remained static, M. smegmatis mc2 155 found to …
Dna Methods To Understand Genetic Variation Of The Mola Mola Populations In And Near Cape Cod, Jessica Barros
Dna Methods To Understand Genetic Variation Of The Mola Mola Populations In And Near Cape Cod, Jessica Barros
Honors Program Theses and Projects
The ocean sunfish Mola mola is a frequent summer visitor to the waters off of Southeastern Massachusetts and Cape Cod. In late fall, water temperatures drop and some animals strand on area beaches. Stranded animals provide an easily available source of DNA to study the population genetics of this species with the specific goal to learn about genetic variation within and between individuals in this population. This study will continue to identify and characterize microsatellite repeat regions that will be used to study genetic variation. Four new microsatellite regions have been identified and amplified using polymerase chain reaction conditions that …
The Effects Of Meloidogyne Incognita On Jaz1, Jaz12, And Jaz13 Gene Expression In Arabidopsis, Emily Green
The Effects Of Meloidogyne Incognita On Jaz1, Jaz12, And Jaz13 Gene Expression In Arabidopsis, Emily Green
Honors Program Theses and Projects
Meloidogyne incognita, a root-knot nematode (RKN), poses a threat to the well-being of the global agricultural industry. These endoparasites rely on plant roots and drain nutrients from crops intended for human or livestock consumption. Root knot nematodes cost the agricultural industry billions of dollars in lost crops each year and threaten efforts to meet the growing demand for food. Though plants are susceptible to dangers, such as these parasites, many have evolved defense and/or repair mechanisms to compensate for this vulnerability. The goal of this research is to study one gene family involved in such defenses. Specifically, I studied the …
Bringing Science To Life In The Fifth-Grade Classroom Through Hands-On Learning, Kelly Gately
Bringing Science To Life In The Fifth-Grade Classroom Through Hands-On Learning, Kelly Gately
Honors Program Theses and Projects
Science helps provide insight into the unknown and provides an outlet for exploration of living things. Children are innately curious about how thing work, and they are eager to ask questions. Science is the perfect outlook for students to fully engage in their inquisitiveness, but yet, many classrooms are skipping over science lessons or choosing to heavily focus on other subjects, such as reading and writing. Science is often taught as an elective, integrated with other subjects or it is only focused on for a short period of time. Unfortunately, when this subject does receive attention, lessons are heavily text-book …
Pyy3-36 Efficacy Is Independent Of Photoperiod But Dependent On Time Of Day, Marissa Maroni
Pyy3-36 Efficacy Is Independent Of Photoperiod But Dependent On Time Of Day, Marissa Maroni
Honors Program Theses and Projects
Approximately 70% of Americans are overweight or obese and studies have shown that poverty-dense American counties are the most prone to obesity (Levine, 2011). Along with diet, the endogenous circadian rhythms have been found to be an important piece of human metabolic health. Circadian disruption in humans, such as jet-lag and shift work, have been linked to metabolic problems such as Type 2 Diabetes Mellitus and Metabolic Syndrome. Since circadian disruption affects many demographics including shift workers and routine business travelers it is imperative to understand the biological mechanism behind the relationship between circadian disruption and weight gain. One potential …
Advanced Cell And Molecular Biology I Cmb 501, Michael Cerbo
Advanced Cell And Molecular Biology I Cmb 501, Michael Cerbo
Library Impact Statements
No abstract provided.
Advanced Cell & Molecular Biology Ii Cmb 502, Michael Cerbo
Advanced Cell & Molecular Biology Ii Cmb 502, Michael Cerbo
Library Impact Statements
No abstract provided.
Investigating The Effects Of Cancer Mutations On The Activity Of P300, Meghan Hall
Investigating The Effects Of Cancer Mutations On The Activity Of P300, Meghan Hall
Spring Showcase for Research and Creative Inquiry
Investigating the effects of cancer mutations on the activity of p300
The Use Hela Derived Telomerase On Nk Cells In The Treatment Of Ovarian Cancer, Juwairyah Gunter
The Use Hela Derived Telomerase On Nk Cells In The Treatment Of Ovarian Cancer, Juwairyah Gunter
Spring Showcase for Research and Creative Inquiry
A research proposal for a novel immunotherapy for treating ovarian cancer.
Ability Of Flavonoids To Mimic The Estrogen Receptor To Drive Myeloid Derived Suppressor Cell Differentiation, Megan Bland, Cecilie Elliott, Kathryn Kosiorek
Ability Of Flavonoids To Mimic The Estrogen Receptor To Drive Myeloid Derived Suppressor Cell Differentiation, Megan Bland, Cecilie Elliott, Kathryn Kosiorek
Spring Showcase for Research and Creative Inquiry
Flavonoids are natural compounds found in dietary elements such as soy, grains, and vegetables that have the potential to bind to the estrogen receptor. Activation of the estrogen receptor drives myeloid derived suppressor cell (MDSC) accumulation, cells that increase during cancer, inflammation, and infection. In this study, we are investigating specific flavonoids, such as epigallocatechin-3-gallate (EGCG), kaempferol, naringenin, daidzein, and genistein, for their ability to mimic estrogen. After examination, we expect that MDSC differentiation will decrease upon treatment of the chosen flavonoids, leading to reduced carcinogenic effects.
Zero Textbook Cost Syllabus For Env 3009/4900 (Conservation Biology And Sustainable Development), Stephen Gosnell
Zero Textbook Cost Syllabus For Env 3009/4900 (Conservation Biology And Sustainable Development), Stephen Gosnell
Open Educational Resources
Conservation biology is an interdisciplinary topic that explores how we can protect and maintain natural areas. Due to the resources we take and impacts we have on natural environments, this field is directly related to restoration ecology (restoring natural areas) and sustainable development/natural resource management. We will explore the basis for these related fields from an ecological, social, legal, and cultural perspective, as all conservation and management projects take place in the larger human landscape. We will consider how we measure biodiversity, why it matters, why is it is threatened, and how we can manage (protect, restore, maintain, use) it …
H/L Ratio As A Measurement Of Immune Function In Terrapene Ornata Species, Vesa Govori
H/L Ratio As A Measurement Of Immune Function In Terrapene Ornata Species, Vesa Govori
Honors Theses
White blood cells are a key part of the immune system, and changes in white cell count can reveal the overall state of health and the immune systems functional ability of a species. White blood such as heterophils and lymphocytes are essential for being able to fight off infections. Analyzing different cell ratios has been commonly done before as a way to observe immune function in bird species as well as other species. Understanding that there are different functions between the different white blood cells provides an extra interesting perspective to what could be happening in the immune system function …
Student Perceptions Of Reasons For Lecture And Active Learning, Calan Koch
Student Perceptions Of Reasons For Lecture And Active Learning, Calan Koch
Honors Theses
With perceived student resistance to active learning in the classroom, instructors are hesitant to implement such methods into their classroom structure despite how effective they may be. This research seeks to understand student perceptions related to the transition to higher prevalence of active learning techniques. We aimed to find answers to how students perceive the ideal classroom to be structured, what reasons they perceive for lecture and active learning components, and possible explanations to concerns of groupwork during class time. We analyzed 64 interviews with undergraduate biology students at the University of Nebraska- Lincoln, developed coding rubrics from commonly found …
Intertidal Ecology Bio 416, Michael Cerbo
Intertidal Ecology Bio 416, Michael Cerbo
Library Impact Statements
No abstract provided.
Student-Faculty Collaborative Research Grant Report, Megan Bestwick
Student-Faculty Collaborative Research Grant Report, Megan Bestwick
Post-Grant Reports
Mitochondria are essential organelles in most eukaryotic cells because of their role in metabolism and the production of ATP by the oxidative phosphorylation (OXPHOS) pathway, as well as other key cellular processes. Metal cofactors, such as copper (Cu) and iron (Fe), are incorporated into OXPHOS protein complexes of yeast located within the inner membrane of the mitochondria. Misincorporation or modulation of these available metals in mitochondrial enzymes leads to the production of reactive oxygen species (ROS). ROS are reactive molecules containing oxygen such as peroxides, superoxide, and hydroxyl radicals. Yeast are a good model for studying aging and the effect …
The Social Construction Of Life: Critical Thinking About Biology In Society, Peter J. Taylor
The Social Construction Of Life: Critical Thinking About Biology In Society, Peter J. Taylor
Working Papers on Science in a Changing World
This book aims to expand the boundaries of the influences that readers consider when interpreting the practices and products of the life sciences ("biology") and their impact on society. The chapter topics include: Interpreting Ideas of Nature; The structure of origin stories; Multiple layers in influencing an audience: The case of Darwin's On the Origin of Species; Metaphors of coordination and development; What causes a disease?—the consequences of hereditarianism in the case of pellagra; How changeable are IQ test scores?; Social negotiations around genetic screening; Intersecting processes involving genes and environment.
Each chapter consists of 5 parts:
1. Introduce simple …
Betting & Hierarchy In Paleontology, Leonard Finkelman
Betting & Hierarchy In Paleontology, Leonard Finkelman
Faculty Publications
In his Rock, Bone, and Ruin: An Optimist’s Guide to the Historical Sciences, Adrian Currie argues that historical scientists should be optimistic about success in reconstructing the past on the basis of future research. This optimism follows in part from examples of success in paleontology. I argue that paleontologists’ success in these cases is underwritten by the hierarchical nature of biological information: extinct organisms have extant analogues at various levels of taxonomic, ecological, and physiological hierarchies, and paleontologists are adept at exploiting analogies within one informational hierarchy to infer information in another. On this account, fossils serve the role …
Lifelines Winter 2019, Southern Adventist University
Lifelines Winter 2019, Southern Adventist University
Lifelines - Biology Department Newsletter
The Winter 2019 issue of Lifelines contains articles on student missions in Micronesia, an alumni spotlight, and a pictorial directory of the 2019 biology and allied health graduates.
Phylogenetic, Genomic, And Biogeographic Characterization Of Anovel And Ubiquitous Marine Invertebrate-Associated Rickettsiales Parasite,Candidatus Aquarickettsia Rohweri, Gen. Nov., Sp. Nov, J. Grace Klinges, Stephanie M. Rosales, Ryan Mcminds, Koty H. Sharp
Phylogenetic, Genomic, And Biogeographic Characterization Of Anovel And Ubiquitous Marine Invertebrate-Associated Rickettsiales Parasite,Candidatus Aquarickettsia Rohweri, Gen. Nov., Sp. Nov, J. Grace Klinges, Stephanie M. Rosales, Ryan Mcminds, Koty H. Sharp
Arts & Sciences Faculty Publications
Bacterial symbionts are integral to the health and homeostasis of invertebrate hosts. Notably, members of the Rickettsiales genus Wolbachia influence several aspects of the fitness and evolution of their terrestrial hosts, but few analogous partnerships have been found in marine systems. We report here the genome, phylogenetics, and biogeography of a ubiquitous and novel Rickettsiales species that primarily associates with marine organisms. We previously showed that this bacterium was found in scleractinian corals, responds to nutrient exposure, and is associated with reduced host growth and increased mortality. This bacterium, like other Rickettsiales, has a reduced genome indicative of a parasitic …
Selective Distant Electrostimulation By Synchronized Bipolar Nanosecond Pulses, Elena C. Gianulis, Maura Casciola, Carol Zhou, Enbo Yang, Shu Xiao, Andrei G. Pakhomov
Selective Distant Electrostimulation By Synchronized Bipolar Nanosecond Pulses, Elena C. Gianulis, Maura Casciola, Carol Zhou, Enbo Yang, Shu Xiao, Andrei G. Pakhomov
Bioelectrics Publications
A unique aspect of electrostimulation (ES) with nanosecond electric pulses (nsEP) is the inhibition of effects when the polarity is reversed. This bipolar cancellation feature makes bipolar nsEP less efficient at biostimulation than unipolar nsEP. We propose to minimize stimulation near pulse-delivering electrodes by applying bipolar nsEP, whereas the superposition of two phase-shifted bipolar nsEP from two independent sources yields a biologically-effective unipolar pulse remotely. This is accomplished by electrical compensation of all nsEP phases except the first one, resulting in the restoration of stimulation efficiency due to cancellation of bipolar cancellation (CANCAN-ES). We experimentally proved the CANCAN-ES paradigm by …