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Full-Text Articles in Life Sciences
Prenataland Newborn Immunoglobulin Levels From Mother-Child Pairs And Risk Of Autismspectrum Disorders, Judith K. Grether, Paul Ashwood, Judy Van De Water, Robert H. Yolken, Meredith C. Anderson, Anthony T. Torres, Jonna B. Westover, Aimee G. Tallian, Robin L. Hansen, Martin Kharrazi, Lisa A. Croen
Prenataland Newborn Immunoglobulin Levels From Mother-Child Pairs And Risk Of Autismspectrum Disorders, Judith K. Grether, Paul Ashwood, Judy Van De Water, Robert H. Yolken, Meredith C. Anderson, Anthony T. Torres, Jonna B. Westover, Aimee G. Tallian, Robin L. Hansen, Martin Kharrazi, Lisa A. Croen
Biology Faculty Publications
Background: An etiological role for immune factors operating during early brain development in children with autism spectrum disorders (ASD) has not yet been established. A major obstacle has been the lack of early biologic specimens that can be linked to later diagnosis. In a prior study, we found lower risk of ASD associated with higher levels of maternally-derived total IgG and Toxoplasmosis gondii (Toxo) IgG in newborn blood spot specimens from children later diagnosed with ASD compared to population controls. Methods: We obtained maternal mid-gestational serum specimens and newborn screening blood spots from the California Genetics Disease Screening Program (GDSP) …