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Articles 1 - 10 of 10

Full-Text Articles in Life Sciences

Lis1 And Ndel1 Influence The Timing Of Nuclear Envelope Breakdown In Neural Stem Cells, Sachin Hebbar, Mariano T. Mesngon, Aimee M. Guillotte, Bhavim Desai, Ramses Ayala, Deanna S. Smith Sep 2008

Lis1 And Ndel1 Influence The Timing Of Nuclear Envelope Breakdown In Neural Stem Cells, Sachin Hebbar, Mariano T. Mesngon, Aimee M. Guillotte, Bhavim Desai, Ramses Ayala, Deanna S. Smith

Faculty Publications

Lis1 and Ndel1 are essential for animal development. They interact directly with one another and with cytoplasmic dynein. The developing brain is especially sensitive to reduced Lis1 or Ndel1 levels, as both proteins influence spindle orientation, neural cell fate decisions, and neuronal migration. We report here that Lis1 and Ndel1 reduction in a mitotic cell line impairs prophase nuclear envelope (NE) invagination (PNEI). This dyneindependent process facilitates NE breakdown (NEBD) and occurs before the establishment of the bipolar spindle. Ndel1 phosphorylation is important for this function, regulating binding to both Lis1 and dynein. Prophase cells in the ventricular zone (VZ) …


Peer Review In An Undergraduate Biology Curriculum: Effects On Students’ Scientific Reasoning, Writing And Attitudes, Briana Eileen Timmerman Mar 2008

Peer Review In An Undergraduate Biology Curriculum: Effects On Students’ Scientific Reasoning, Writing And Attitudes, Briana Eileen Timmerman

Faculty Publications

Scientific reasoning and writing skills are ubiquitous processes in science and therefore common goals of science curricula, particularly in higher education. Providing the individualized feedback necessary for the development of these skills is often costly in terms of faculty time, particularly in large science courses common at research universities. Past educational research literature suggests that the use of peer review may accelerate students’ scientific reasoning skills without a concurrent demand on faculty time per student. Peer review contains many elements of effective pedagogy such as peer-peer collaboration, repeated practice at evaluation and critical thinking, formative feedback, multiple contrasting examples, and …


A Call For A Statewide Bioinformatics Institute, John R. Rose Jan 2008

A Call For A Statewide Bioinformatics Institute, John R. Rose

Journal of the South Carolina Academy of Science

No abstract provided.


Sc Inbre: A Catalyst For Biomedical Research Development In South Carolina, Lucia A. Pirisi-Creek M.D, Scott Little, Ph.D. Jan 2008

Sc Inbre: A Catalyst For Biomedical Research Development In South Carolina, Lucia A. Pirisi-Creek M.D, Scott Little, Ph.D.

Journal of the South Carolina Academy of Science

No abstract provided.


Inflammation: The Key To Health And Disease, Prakash Nagarkatti Ph. D, Donald J. Dipette M. D. Jan 2008

Inflammation: The Key To Health And Disease, Prakash Nagarkatti Ph. D, Donald J. Dipette M. D.

Journal of the South Carolina Academy of Science

No abstract provided.


Editorial, First Science And Policy Issue, Jscas Jan 2008

Editorial, First Science And Policy Issue, Jscas

Journal of the South Carolina Academy of Science

No abstract provided.


With The Help Of South Carolina Research Universities, Scra Demonstrates Leadership In Applied Research And Commercialization Within Sc, Bill Mahoney Jan 2008

With The Help Of South Carolina Research Universities, Scra Demonstrates Leadership In Applied Research And Commercialization Within Sc, Bill Mahoney

Journal of the South Carolina Academy of Science

No abstract provided.


Thermoelectric Applications For Imaging Infrared Focal Plane Arrays, Roy T. Littleton Jan 2008

Thermoelectric Applications For Imaging Infrared Focal Plane Arrays, Roy T. Littleton

Journal of the South Carolina Academy of Science

No abstract provided.


Solution Chemical Synthesis Of Nanostructured Thermoelectric Materials, Xiaohua Ji, Terry M. Tritt, Xinbing Zhao, Joe W. Kolis Jan 2008

Solution Chemical Synthesis Of Nanostructured Thermoelectric Materials, Xiaohua Ji, Terry M. Tritt, Xinbing Zhao, Joe W. Kolis

Journal of the South Carolina Academy of Science

No abstract provided.


Phonon Scattering Effects On Thermal Conductivity Of Tinisn-Based Half-Heusler Alloys, S. Bhattacharya, T. M. Tritt, M. J. Skove, M. Russell, S. J. Poon, V. Ponnambalam, Y. Xia, N. Thadhani Jan 2008

Phonon Scattering Effects On Thermal Conductivity Of Tinisn-Based Half-Heusler Alloys, S. Bhattacharya, T. M. Tritt, M. J. Skove, M. Russell, S. J. Poon, V. Ponnambalam, Y. Xia, N. Thadhani

Journal of the South Carolina Academy of Science

No abstract provided.