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Full-Text Articles in Life Sciences
Why We Can’T Solve The Opioid Problem, Wayne F. Coombs, Ph.D.
Why We Can’T Solve The Opioid Problem, Wayne F. Coombs, Ph.D.
Journal of Appalachian Health
Appalachia’s opioid epidemic is a complex, systemic problem being addressed by limited intervention processes conceptualized through narrow disciplinary models that are not working. We need a new comprehensive, collaborative approach if we ever hope to find solutions to this problem.
Incidence Of West Nile Virus In House Sparrow Nestlings In Relation To Parental Effort, Natalie Mickelsen
Incidence Of West Nile Virus In House Sparrow Nestlings In Relation To Parental Effort, Natalie Mickelsen
Kaleidoscope
The house sparrow, Passer domesticus, is known to be an important host of West Nile (WN) virus and may contribute to the transmission of WN virus to humans. However, little is known about the factors that influence the occurrence of WN virus in birds. I conducted a study to determine if parental care was related to the rates of WN virus infections among nestling birds. I observed house sparrow nests for one hour periods noting the time the male and female parent spent on the nest box, in the nest box, and the number of food trips, as measures …
Oswald Biological Sciences First Place: Development Of Three-Dimensional Lung Multicellular Spheroids In Air And Liquid Interface Culture For The Evaluation Of Anti-Cancer Therapeutics, Alexandra Tsoras
Kaleidoscope
The implementation of in vitro results to in vivo applications has limitations due to conventional two-dimensional (2D) in vitro conditions lacking the ability to create a physiologically representative model. This study investigated a three-dimensional (3D) cell culture technique to model lung tumors in vitro. A 3D lung cancer model was created by applying collagen (a semi-non-adhesive material) to a transwell, which allowed for nutrient transfer through the collagen. Two lung cancer cells lines (H358, a bronchioalveolar carcinoma and A549, a lung adenocarcinoma) were seeded on top of the collagen. The non-adhesive collagen allowed the cells to preferentially attach to one …
Oswald Biological Sciences Second Place: Rna Degradation Is Elevated With Age-, But Not Disuse-Associated Skeletal Muscle Atrophy, Aman Shah
Kaleidoscope
Aging and inactivity are both associated with decreased muscle size and protein content. The possible role of RNA degradation in the loss of protein has not yet been investigated. Therefore, we hypothesized that RNA degradation was elevated with muscle atrophy in aging and disuse. Brown Norway/Fisher344 male rats at 6 and 32 months were hindlimb suspended (HS) for 14 days to induce muscle atrophy or remained weight bearing (WB). Cytosolic extracts from gastrocnemius muscles were prepared for Western analysis of DCP-2 protein (marker of p-bodies) and RNA degradation assay. In vitro total RNA decay assay was performed using 30ug of …
Anorexia, Bulimia, And Crayfish (Or, Why I Study The Pharmacology Of Serotonin Receptors In Glutamatergic Invertebrate Systems), Garrett Sparks
Anorexia, Bulimia, And Crayfish (Or, Why I Study The Pharmacology Of Serotonin Receptors In Glutamatergic Invertebrate Systems), Garrett Sparks
Kaleidoscope
No abstract provided.