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Full-Text Articles in Life Sciences

Drosophila Nanoparticle Toxicity Model, Mark Nielsen Dec 2008

Drosophila Nanoparticle Toxicity Model, Mark Nielsen

Mark G. Nielsen

Department of Defense Consortium Research Fellows Program, $120,000 (2009-2012). Research Assistantship funding for my Ph.D. student Ryan Posgai, who developed the Drosophila nanoparticle toxicity model


Nanoparticle Toxicity Tests In Model Systems, Mark Nielsen Dec 2007

Nanoparticle Toxicity Tests In Model Systems, Mark Nielsen

Mark G. Nielsen

Nielsen, M. G. (Co-Principal), Rowe, J. J. (Principal), Robinson, J. B. (Co-Principle), Hong, T. (Co-Principal), "Nanoparticle Toxicity Tests in Model Systems," National Science Foundation G07R20573, $400,000.00 (2008 - 2010). We developed and applied multiple models (tissue culture, microbial, organismal) to test the toxicity of nanoparticles. I am responsible for the organismal (Drosophila) model.


Development And Characterization Of Ruthenium-Substituted Porphyrins, Mark Nielsen Dec 2005

Development And Characterization Of Ruthenium-Substituted Porphyrins, Mark Nielsen

Mark G. Nielsen

Nielsen, M. G. (Co-Principal), Swavey, S. M. (Principal), Hong, Y. (Principal), Masthay, M. B. (Co-Principal), Robinson, J. B. (Co-Principal), "Development and Characterization of Ruthenium-substituted Porphyrins," Interdisciplinary Undergraduate Research Program American Association for the Advancement of Science/Merck Pharmaceuticals, $60,000.00 (2006 - 2009). We created an interdisciplinary, undergraduate research program to develop and test porphyrin-based photodynamic therapies. I am responsible for DNA-based assays of porphyrin cleavage activity, and development of the Drosophila IR model.


Developmental Constraint In Spermtail Evolution, Mark Nielsen Dec 2002

Developmental Constraint In Spermtail Evolution, Mark Nielsen

Mark G. Nielsen

Nielsen, M. G. (Principal), "Developmental Constraint in Spermtail Evolution," National Science Foundation MCB-0316359, $170,000.00 (2003 - 2007). We determined that the mode and tempo of insect tubulin evolution is dictated by the rate of production of heritable variants, not competition among tubulin alleles.