Life Sciences Commons^™

Ict For Poverty Alleviation In Pacific Island Nations: Study Of Icts4d In Fiji, Deogratias Harorimana, Opeti Rokotuinivono, Emali Sewale, Fane Salaiwai, Marica Naulu, Evangelin Roy

Dr Deogratias Harorimana

ICT for Poverty Alleviation in Pacific Island Nations: Study of ICTs4D in Fiji There has been a vague and little knowledge on the role or potential of Information and Communications Technologies (ICTs) in relation to addressing poverty in Fiji. This may be probably due to the newness of the technology in the South Pacific Region as a whole but also probably due to the fact that only 9.7% of the current Fiji 931,000 populations are internet users (ITC Figures 2011). This paper reports on finding how ICTs is contributing towards poverty alleviation in Fiji. On the basis of reviewed best …

Two Different High Throughput Sequencing Approaches Identify Thousands Of De Novo Genomic Markers For The Genetically Depleted Bornean Elephant., Reeta Sharma, Benoit Goossens, Benoit Goossens, Célia Kun-Rodrigues, Tatiana Teixeira, Nurzhafarina Othman, Nurzhafarina Othman, Jason Q. Boone, Nathaniel K. Jue, Craig Obergfell, Rachel J. O'Neill, Lounès Chikhi, Lounès Chikhi, Lounès Chikhi

Nathaniel Jue

Inhibition Of Herpes Simplex Virus Type 1 With The Modified Green Tea Polyphenol Pamitoyl-Epigallocatechin Gallate., Aline De Oliveira, Sandra Adams, Lee Lee, Sean Murray, Stephen Hsu, Jeffrey Hammond, Douglas Dickinson, Ping Chen, Tin-Chun Chu

Tin-Chun Chu, Ph.D.

No abstract provided.

Epigallocatechin-3-Gallate Modulates Oxidative Stress In Exocrine Glands Of A Primary Sjogren’S Syndrome Mouse Model Prior To Disease Onset, Seiji Ohno, Hongfang Yu, Douglas Dickinson, Tin-Chun Chu, Kalu Ogbureke, Scott Derossi, Tetsuya Yamamoto, Stephen Hsu

Tin-Chun Chu, Ph.D.

No abstract provided.

How Can Pacific Island Economies Benefits From The Advent Of Ict’S – Review Of Best Practices In Education, Deogratias Harorimana Sr

Dr Deogratias Harorimana

This paper explored implementation and use of information and communication technologies in Fiji, in order to gain insight into recent government initiatives to introduce computers and other ICTs for the community of Fiji. The focus of this paper in that it provided the framework for an in-depth exploration of e-learning centers around the country and the benefits from the advent of ICT’s in e-learning community centers in Fiji. Areas concentrated on are outcome of ICT’s in formal education to students and community as a whole in areas of agriculture, health, environment and infrastructure etc. The research sought understanding from the …

Technical Assistance, Knowledge Gatekeeping And Indigenous Knowledge: Re-Thinking The International Development Practice, Deogratias Harorimana Sr

Dr Deogratias Harorimana

This paper presents results from a multi-disciplinary conceptual analysis of development theory and practice. It reviews issues raised and proposes a shift in the epistemology of possession towards an epistemology of practice which is guided by the following aspects (1) The consideration of the learning culture of parties involved, (2) the ability and willingness for decontextualisation of the knowledge by the source and (3) the ability to embedded it by recipients (embededness ), (4) the importance that is attached to knowledge of the host country as reflected through (5) Similarity in culture, values, understanding of context and knowledge bases; (6) …

Protamine-Like Proteins In 12 Sequenced Species Of Drosophila, Zain Alvi, Tin-Chun Chu, Valerie Schawaroch, Angela Klaus

Tin-Chun Chu, Ph.D.

No abstract provided.

Identification And Bioinformatic Analyses Of Vanillate Operon In Cyanobacterium Synechococcus Sp. Iu 625, Robert Newby, Tin-Chun Chu

Tin-Chun Chu, Ph.D.

No abstract provided.

Bioinformatic Analysis Of Cyanobacterial Mercuric Resistance Genes And Identification Of Synechococcus Sp. Iu 625 Putative Mercuric Resistance Genes, Lee Lee, Chiedozie Okafor, Matthew Rienzo, Tin-Chun Chu

Tin-Chun Chu, Ph.D.

No abstract provided.

Proteomic Analysis Of 17Β-Estradiol Degradation By Stenotrophomonas Maltophilia, Zhongtian Li

Z Li

Microbial degradation plays a critical role in determining the environmental fate of steroid hormones, such as 17β-estradiol (E2). The molecular mechanisms governing the microbial transformation of E2 and its primary degradation intermediate, estrone (E1), are largely unknown. The objective of this study was to identify metabolism pathways that might be involved in microbial estrogen degradation. To achieve the objective, Stenotrophomonas maltophilia strain ZL1 was used as a model estrogen degrading bacterium and its protein expression level during E2/E1 degradation was studied using quantitative proteomics. During an E2 degradation experiment, strain ZL1 first converted E2 to E1 stoichiometrically. At 16 h …

Mis Mock Questions (Why Mis In Corporate Turbulant Times), Deogratias Harorimana Sr

Dr Deogratias Harorimana

With corporate strategy becoming more and more dependent on speed,focus, innovation and strategy, what can MIS do? and what should be MIS role ? what is the relationship between Corporate Strategy KPI and MIS? These questions are answered in an MBA Management Information Systems at USP. This programme is delivered across the entire Pacific region through the Graduate School of Business. It is my privilege to post here few questions that students who attended one of the course in Nadi, at Tanoa International Hotel had to answer in one of the Quiz test.

Economic Benefits Analysis Of Mining Industries In Png And Solomon Islands, Deogratias Harorimana Sr

Dr Deogratias Harorimana

This paper discusses mining and mineral operations in the two countries Papua New Guinea and Solomon Islands with regards to its contribution to the overall Gross domestic Product and the economic development of each country.

Our finding shows that mining is an excellent contributor to economic growth and development as in the case of Papua New Guinea.Tax revenue from PNG Mining industries contributions to the PNG fiscal basket remains strong and growing steadily. The mining and minerals tax revenue remains an important contributor to the government fiscal budget over the last 10 years. This has been a strong contributor to …

Understanding Economics Of The Pacific Island Nations: Issues And Cases, Deogratias Harorimana Sr

Dr Deogratias Harorimana

No abstract provided.

Job Creation In The Tuna Industry Of The Solomon Islands- A Tentative Strategic Analysis, Deogratias Harorimana Sr

Dr Deogratias Harorimana

The principal objective of this paper is to review the current Tuna Fisheries Policies in the Solomon Islands with a view to proposing strategies that will maximize Job creation while at the same time address the issues that currently exist in this sector. Although the Tuna Industry’s contribution to GDP is quite significant, the Solomon Island Government (SIG) gets little or close to nothing out of it in the form of revenue and Job creation with the majority of vessels being foreign owned and fishing license fees amongst the lowest in the Pacific. SOLTAI which is partly owned by the …

A Novel Topology For Representing Protein Folds, Mark R. Segal

Mark R Segal

Various topologies for representing three dimensional protein structures have been advanced for purposes ranging from prediction of folding rates to ab initio structure prediction. Examples include relative contact order, Delaunay tessellations, and backbone torsion angle distributions. Here we introduce a new topology based on a novel means for operationalizing three dimensional proximities with respect to the underlying chain. The measure involves first interpreting a rank-based representation of the nearest neighbors of each residue as a permutation, then determining how perturbed this permutation is relative to an unfolded chain. We show that the resultant topology provides improved association with folding and …

Review Of Solomon Islands’ Policies And Programs To Promote Private Sector Development And Small Business, Deogratias Harorimana Sr

Dr Deogratias Harorimana

Solomon Islands is a nation with vast resources with huge potential to excel economically if proper business atmosphere is provided for both private sector development and small and medium enterprises entrepreneurship. Conducive policies that, not only, a mere statement but is broken down to workable strategies with quantitative expected outcome with a strong mentoring mechanism is very important. Previous governments have continuously ignored the importance of having small business policies until lately when NCRA government came up with a set of policies that strategically addresses the significance of small and medium businesses. However, notwithstanding foreign investment is very important in …

Phylogenetics Of Morus (Moraceae) Inferred From Its And Trnl-Trnf Sequence Data., Madhav Nepal

Madhav Nepal

Removing 17Β-Estradiol From Drinking Water In A Biologically Active Carbon (Bac) Reactor Modified From A Granular Activated Carbon (Gac) Reactor, Zhongtian Li

Z Li

Estrogenic compounds in drinking water sources pose potential threats to human health. Treatment technologies are needed to effectively remove these compounds for the production of safe drinking water. In this study, GAC adsorption was first tested for its ability to remove a model estrogenic compound, 17β-estradiol (E2). Although GAC showed a relatively high adsorption capacity for E2 in isotherm experiments, it appeared to have a long mass transfer zone in a GAC column reactor, causing an early leakage of E2 in the effluent. With an influent E2 concentration of 20 μg/L, the GAC reactor was able to bring down effluent …

Permutation-Based Pathway Testing Using The Super Learner Algorithm, Paul Chaffee, Alan E. Hubbard, Mark L. Van Der Laan

Paul H. Chaffee

Many diseases and other important phenotypic outcomes are the result of a combination of factors. For example, expression levels of genes have been used as input to various statistical methods for predicting phenotypic outcomes. One particular popular variety is the so-called gene set enrichment analysis (GSEA). This paper discusses an augmentation to an existing strategy to estimate the significance of an associations between a disease outcome and a predetermined combination of biological factors, based on a specific data adaptive regression method (the "Super Learner," van der Laan et al., 2007). The procedure uses an aggressive search procedure, potentially resulting in …

Comparative Sequence Analysis Of Fatty Acid Desaturase 2 (Fad2) Cdna Sequences From The Compositae [Asteraceae], Paul Ames Muller Jr.

Paul Muller

Fatty acid desaturases are enzymes capable of modifying carbon-carbon bonds within fatty acids. All higher plants contain one or more oleic acid desaturases that catalyze insertion of a double bond between carbons 12 and 13 of oleic acid to produce linoleic acid, an unsaturated fatty acid. However, this family of enzymes may vary in specificity and are responsible for a wide spectrum of unsaturated fatty acids found in nature that play important ecological, physiological, and industrial roles. Here, I examine nucleotide sequence evolution and predict structural changes of translated expressed Fatty Acid Desaturase 2 (FAD2) cDNA sequences in the Compositae …

Description And Annotation Of Biomedical Data Sets, Jen Ferguson

Jen Ferguson

Deposition of biomedical data sets is on the rise as more scientists submit experimental data to accompany their publications. Scientists are also increasingly reusing these publicly available data sets in their own work. Despite these developments, lack of both context and metadata can create barriers to understanding and repurposing these data sets. Researchers from the Bioinformatics Core Group in the Harvard School of Public Health attempted to address this issue by assembling a team of data curators who used the open source software suite ISA tools to annotate and contextualize microarray data sets. This paper describes the workflow and software …

Social Networks And Web2.0 Among Youth: Lessons For Pacific Island Nations, Deogratias Harorimana Sr

Dr Deogratias Harorimana

This study is on social networks and web2 among youths and the lessons for Pacific Island nation. This study defines commonly used social networking sites used by the Pacific youths, average time spent, reasons behind the use of social networking sites and how social networking sites can be used as a development tool for Pacific Island nation. It was found that the popularity of social networking amongst youths in Pacific Island Countries is fast growing, increasing more than three folds year on year in the last 3years. Social Networks are a vital part of life for PIC youths, where, now …

Disparities In Combination Drug Therapy Use In Older Adults With Coronary Heart Disease: A Cross-Sectional Time-Series In A Nationally Representative Us Sample, Jennifer Tjia, Becky Briesacher, Dawei Xie, Jason Fu, Robert Goldberg

Jennifer Tjia

BACKGROUND: Despite evidence of effective combination drug therapy for secondary prevention of coronary heart disease (CHD), older adults with this condition remain undertreated.

OBJECTIVE: To describe time trends (1992-2003) in the adoption of combination cardiac drug therapies (beta-blockers [beta-adrenoceptor antagonists], ACE inhibitors or angiotensin II type 1 receptor antagonists [angiotensin receptor blockers; ARBs], and lipid-lowering agents) among older adults in the US with CHD and to identify factors associated with not using combination therapy.

METHODS: The study took the form of a cross-sectional time-series. The study population consisted of a nationally representative sample of adults aged >or=65 years with CHD …

Using The Case Study Methodology In Teaching, Deogratias Harorimana Mr

Dr Deogratias Harorimana

This paper reviews the Why, How, to use the Case Study Methods in MBA teaching. The Presentation was prepared for and delivered as part of MBA students induction Programme in the Graduate School of Business.

Statistical Methods For Proteomic Biomarker Discovery Based On Feature Extraction Or Functional Modeling Approaches, Jeffrey S. Morris

Jeffrey S. Morris

In recent years, developments in molecular biotechnology have led to the increased promise of detecting and validating biomarkers, or molecular markers that relate to various biological or medical outcomes. Proteomics, the direct study of proteins in biological samples, plays an important role in the biomarker discovery process. These technologies produce complex, high dimensional functional and image data that present many analytical challenges that must be addressed properly for effective comparative proteomics studies that can yield potential biomarkers. Specific challenges include experimental design, preprocessing, feature extraction, and statistical analysis accounting for the inherent multiple testing issues. This paper reviews various computational …

Integrative Bayesian Analysis Of High-Dimensional Multi-Platform Genomics Data, Wenting Wang, Veerabhadran Baladandayuthapani, Jeffrey S. Morris, Bradley M. Broom, Ganiraju C. Manyam, Kim-Anh Do

Jeffrey S. Morris

Motivation: Analyzing data from multi-platform genomics experiments combined with patients’ clinical outcomes helps us understand the complex biological processes that characterize a disease, as well as how these processes relate to the development of the disease. Current integration approaches that treat the data are limited in that they do not consider the fundamental biological relationships that exist among the data from platforms.

Statistical Model: We propose an integrative Bayesian analysis of genomics data (iBAG) framework for identifying important genes/biomarkers that are associated with clinical outcome. This framework uses a hierarchical modeling technique to combine the data obtained from multiple platforms …

The Evolution Of Cooperation: How Patience Matters, Atin Basu Choudhary, Raja Mazumder, Vahan Simoyan

Atin Basu Choudhary

The evolution of cooperation has been the focus of much attention from evolutionary game theorists. Of course, conventional game theorists often cite the Folk Theorem to suggest that cooperation is very likely as long as people are patient. However, experimental and real world evidence of the Folk Theorem has been sparse. We investigate whether cooperation can evolve endogenously in a population where people have different patience levels. We motivate our model by asking the following question: why don’t biologists cooperate with each other by contributing to biological databases? We apply the Folk theorem from conventional game theory and assume that …

Hslic Fall 2012 Scholarship Committee Report, Ann Jordan

Ann Jordan

No abstract provided.

The Gatekeeper And The Knowledge Environment-Who They Are, How They Work Empirical Evidences From High-Tech Manufacturing And R&D Firms, Deogratias Harorimana

Dr Deogratias Harorimana

Purpose of the Study: The purpose of this study was to critically study the role of the Knowledge Gatekeeper within the manufacturing and high tech selected case studies and by explaining who they are, how they work and identify and analyse the barriers to knowledge creation and knowledge sharing. Methodology: The research was guided by an inductive approach with a multiple case study strategy. Research instruments included a questionnaire and interviews from respectively 105 and 40 respondents. Findings: In the African Manufacturing context, and in absence of sophisticated technologies and highly qualified personnel, technical knowledge can be obtained from organizational …

Review Of Economics Of Manamagement Information Systems, Deogratias Harorimana Sr

Dr Deogratias Harorimana

“Information technology is the "digital nervous system" of any business.” (Bill Gates, Chairman, Microsoft Corporation, 1997)

The way business is conducted in this era is phenomenal. Almost everything is a “click” away. The customers are satisfied, businesses are satisfied, Government is satisfied and the entire globe is gratified by the work of information technology (IT). This research discloses the several returns and shortcomings of IT, and how businesses use IT to realize their strategic goals.

The report presents discussion on two organisations, Dell Computer Corporation and Sydney Waters, which had a prosperous and disastrous implementation of IT systems respectively. The …