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Full-Text Articles in Life Sciences
Tools And Approaches For The Construction Of Knowledge Models From The Neuroscientific Literature, Gully Apc Burns, Arshad M. Khan, Shahram Ghandeharizadeh, Mark O'Neill, Yi-Shin Chen
Tools And Approaches For The Construction Of Knowledge Models From The Neuroscientific Literature, Gully Apc Burns, Arshad M. Khan, Shahram Ghandeharizadeh, Mark O'Neill, Yi-Shin Chen
Arshad M. Khan, Ph.D.
Within this paper, we describe a neuroinformatics project (called "NeuroScholar," http://www.neuroscholar.org/) that enables researchers to examine, manage, manipulate, and use the information contained within the published neuroscientific literature. The project is built within a multi-level, multi-component framework constructed with the use of software engineering methods that themselves provide code-building functionality for neuroinformaticians. We describe the different software layers of the system. First, we present a hypothetical usage scenario illustrating how NeuroScholar permits users to address large-scale questions in a way that would otherwise be impossible. We do this by applying NeuroScholar to a "real-world" neuroscience question: How is stress-related information …
The Problem With The Paleoptera Problem: Sense And Sensitivity, T. Heath Ogden
The Problem With The Paleoptera Problem: Sense And Sensitivity, T. Heath Ogden
T. Heath Ogden
While the monophyly of winged insects (Pterygota) is well supported, phylogenetic relationships among the most basal extant pterygote lineages are problematic. Ephemeroptera (mayflies) and Odonata (dragonflies) represent the two most basal extant lineages of winged insects, and determining their relationship with regard to Neoptera (remaining winged insects) is a critical step toward understanding insect diversification. A recent molecular analysis concluded that Paleoptera (Odonata +Ephemeroptera) is monophyletic. However, we demonstrate that this result is supported only under a narrow range of alignment parameters. We have further tested the monophyly of Paleoptera using additional sequence data from 18SrDNA, 28S rDNA, and Histone …