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Bioinformatics

Master's Projects

Theses/Dissertations

2021

Meta-Analysis

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Meta-Analysis Of Natural Vs Pharmaceutical Interventions For Alzheimer's Disease, Tamara Vrublevskaya Jan 2021

Meta-Analysis Of Natural Vs Pharmaceutical Interventions For Alzheimer's Disease, Tamara Vrublevskaya

Master's Projects

The purpose of this research is to present a way to compare interventions by collecting all available drug clinical trials for a disease of interest. The assessment is done using Meta-Analysis, a method for evaluating data from several studies to arrive at a combined estimate of treatment effect. The evaluation is done in R on a given set of studies to answer the question – which Alzheimer's Disease intervention (pharmaceutical vs. natural) show better outcomes and fewer adverse effects. The research covers many types of interventions across diverse patient populations. On a small subset of papers, natural treatments showed better …