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Life Sciences Commons

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Bioinformatics

Master's Projects

Theses/Dissertations

2021

Immune system.

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Full-Text Articles in Life Sciences

Differential Gene Expression Analysis Of Mice Thymi After Spaceflight, Roshani Codipilly May 2021

Differential Gene Expression Analysis Of Mice Thymi After Spaceflight, Roshani Codipilly

Master's Projects

With increases in space travel and a desire to inhabit the moon and Mars comes a pressing need to understand the impact of spaceflight on the body. Some effects are already known, such as reduced cardiac function and bone loss, but one area that needs to be further explored is the immune system. Differential gene expression analysis of mice thymi was performed to determine the impact of spaceflight on the immune system. The dataset that was analyzed, GLDS-289, was obtained from GeneLab, a space-omics database developed by NASA. Differential gene expression analysis was accomplished using a Nextflow implementation of GeneLab’s …