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Visualization And Interpretation Of Protein Interactions, Dipanjan Chatterjee
Visualization And Interpretation Of Protein Interactions, Dipanjan Chatterjee
Electronic Thesis and Dissertation Repository
Visualization and interpretation of deep learning models' prediction is a very important area of research in machine learning nowadays. Researchers are not only focused on generating a model with good performance, but also they want to trust the model. Our aim in this thesis is to adapt existing interpretation methods to a protein-protein binding site prediction problem to visualize and understand the model's prediction and learning pattern.
We present three deep learning-based interpretation methods: sensitivity analysis, saliency map and integrated gradients to analyze the amino acid residues which create positive and negative relevance to the deep learning models' prediction. As …