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Full-Text Articles in Life Sciences
Orfanid: A Web-Based Search Engine For The Discovery And Identification Of Orphan And Taxonomically Restricted Genes, Richard S. Gunasekera, Komal K.B. Raja, Suresh Hewapathirana, Thushara Galbadage, Emanuel Tundrea, Vinodh Gunasekera, Paul A. Nelson
Orfanid: A Web-Based Search Engine For The Discovery And Identification Of Orphan And Taxonomically Restricted Genes, Richard S. Gunasekera, Komal K.B. Raja, Suresh Hewapathirana, Thushara Galbadage, Emanuel Tundrea, Vinodh Gunasekera, Paul A. Nelson
Faculty Articles & Research
With the multiplicity of genomes sequenced today, it has been shown that significant percentages of genes in any given taxon do not possess orthologous sequences in other taxa. These sequences are typically designated as orphans/ORFans when found as singletons in one species only or taxonomically restricted genes (TRGs) when found at higher taxonomic ranks. Quantitative and collective studies of these genes are necessary for understanding their biological origins. Currently, orphan gene identifying software is limited, and those previously available are either not functional, are limited in their database search range, or are very complex algorithmically. Thus, an interested researcher studying …