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Bioinformatics

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Journal of Undergraduate Research

2017

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Genome-Wide Association Study Of Prolactin In Cerebrospinal Fluid And Plasma, Lorna Sheradyn Hamilton, Dr. John Kauwe Jun 2017

Genome-Wide Association Study Of Prolactin In Cerebrospinal Fluid And Plasma, Lorna Sheradyn Hamilton, Dr. John Kauwe

Journal of Undergraduate Research

Prolactin is the major hormone involved in milk lactation for pregnant women and has been discovered to play a role in a variety of biological functions. Several other functions include the immune system, reproductive system, maternal behavior, insulin production, and stimulating neurogenesis.1 2 Using prolactin levels from both cerebrospinal fluid and blood plasma from nearly 500 individuals, we will be able to conduct a genome-wide association study to identify single-nucleotide polymorphisms (SNPs), which will lead to a better understanding of what genes are playing a significant role in prolactin’s production and regulation.