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Biochemistry, Biophysics, and Structural Biology

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David Bollivar

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Putting Metal In The Middle, David Bollivar Mar 2010

Putting Metal In The Middle, David Bollivar

David Bollivar

Placing metal ions into the center of a porphyrin ring is a significant cellular challenge. Lundqvist et ai. (2010) provide snapshots of the AAA + motor unit of magnesium chelatase, an enzyme that insert magnesium ion into the porphyrin ring accompanied by ATP expenditure, in different states of binding to adenosyl nucleotides.