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Biochemistry, Biophysics, and Structural Biology

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Selected Works

2012

Diet

Articles 1 - 2 of 2

Full-Text Articles in Life Sciences

Consumption Of High Ω-3 Fatty Acid Diet Suppressed Prostate Tumorigenesis In C3(1) Tag Mice, Juliana Akinsete, Gabriela Ion, Theodore Witte, W. Hardman Oct 2012

Consumption Of High Ω-3 Fatty Acid Diet Suppressed Prostate Tumorigenesis In C3(1) Tag Mice, Juliana Akinsete, Gabriela Ion, Theodore Witte, W. Hardman

Gabriela Ion

Prostate cancer incidence and mortality are high in the Western world and high ω-6/ω-3 PUFA in the Western diet may be a contributing factor. We investigated whether changing from a diet that approximates ω-6 fat content of the Western diet to a high ω-3 fat diet at adulthood might reduce prostate cancer risk. Female SV 129 mice that had consumed a high ω-6 diet containing corn oil for 2 weeks were bred with homozygous C3(1)Tag transgenic male mice. All male offspring were weaned to the corn oil diet (CO) until postpuberty when half of the male offspring were transferred to …


Microwear, Mechanics And The Feeding Adaptations Of Australopithecus Africanus, Paul Constantino, Craig Byron, Paul Dechow, Ian Gross, Peter Lucas, Brian Richmond, Callum Ross, Dennis Slice, Mark Spencer, Dennis Strait, Qian Wang, Gerhard Weber, Bernard Wood, Barth Wright Sep 2012

Microwear, Mechanics And The Feeding Adaptations Of Australopithecus Africanus, Paul Constantino, Craig Byron, Paul Dechow, Ian Gross, Peter Lucas, Brian Richmond, Callum Ross, Dennis Slice, Mark Spencer, Dennis Strait, Qian Wang, Gerhard Weber, Bernard Wood, Barth Wright

Paul J. Constantino

Recent studies of dental microwear and craniofacial mechanics have yielded contradictory interpretations regarding the feeding ecology and adaptations of Australopithecus africanus. As part of this debate, the methods used in the mechanical studies have been criticized. In particular, it has been claimed that finite element analysis has been poorly applied to this research question. This paper responds to some of these mechanical criticisms, highlights limitations of dental microwear analysis, and identifies avenues of future research.