Life Sciences Commons^™

Dimerization Of Neural Cadherin In The Presence Of Low Calcium, Kyler Pisciotta

Honors Theses

Cell-cell linkage is a necessity for proper tissue function and stability in many biological systems. One moiety that allows for the proper linking of cells to one another is a family of molecules known as cadherins. This family of proteins can be found within the membrane of many different types of cells and the extracellular portions of the cadherin proteins interact with those of other cells to link adjacent cells together via the formation of a dimer complex. The presence of calcium (Ca²⁺) is of crucial importance for the formation of this cadherin dimer. In this study, we …