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Full-Text Articles in Life Sciences
Synthesis, Characterization And Mechanistic Studies Of Biomolecules@Mesomofs, Yao Chen
Synthesis, Characterization And Mechanistic Studies Of Biomolecules@Mesomofs, Yao Chen
USF Tampa Graduate Theses and Dissertations
Encapsulation of biomolecules is of great interest to research advances related to biology, physiology, immunology, and biochemistry, as well as industrial and biomedical applications such as drug delivery, biocatalysis, biofuel, food and cosmetics. Encapsulation provides functional characteristics that are not fulfilled by free biomolecules and stabilizes the fragile biomolecules. In terms of biocatalysis, solid support can often enhance the stability of enzymes, as well as facilitate separation and recovery for reuse while maintaining activity and selectivity. Various kinds of materials have been used for encapsulation of biomolecules, among which, porous materials are an important group. Metal-organic frameworks (MOFs) have attracted …
Amino Acid Racemase Enzyme Assays, Atanas D. Radkov, Luke A. Moe
Amino Acid Racemase Enzyme Assays, Atanas D. Radkov, Luke A. Moe
Plant and Soil Sciences Faculty Publications
Amino acid racemases are enzymes that invert the α-carbon stereochemistry of amino acids (AAs), interconverting amino acids between their L- and D-enantiomers in a reversible reaction. In bacteria, they are known to have catabolic physiological functions but are also involved in the synthesis of many D-AAs, including D-glutamate and D-alanine, which are necessary components of the peptidoglycan layer of the bacterial cell wall. As such, amino acid racemases represent significant targets for the development of bactericidal compounds. Amino acid racemases are also regarded by the biotechnological industry as important catalysts for the production of economically relevant D-AAs. Here, we provide …