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Full-Text Articles in Life Sciences
Molecular Signatures Of Calpain 10 Isoforms Sequences, Envisage Functional Similarity And Therapeutic Potential, Bushra Chaudhry, Farina Hanif, Kausar Saboohi
Molecular Signatures Of Calpain 10 Isoforms Sequences, Envisage Functional Similarity And Therapeutic Potential, Bushra Chaudhry, Farina Hanif, Kausar Saboohi
Department of Biological & Biomedical Sciences
Calpain 10 plays a role in insulin secretion, action and susceptibility to type 2 diabetes. The mechanism through which it influences the insulin secretion and action is not completely defined. A structural bioinformatics approach is applied to envision its mechanism of action using available tools on NCBI (blastp and blastn), EMBL-EBI, Ensembl, Swiss Model Repository websites, I-TASSER, PROCHECK program and Discovery Studio software. Homology of domain I and II of calpain10 (isoform a) was established with super family cysteine proteinase domains (II a and II b, e=1.30e-77, 1.00e-20). Remaining sequences of domain III and T from (isoform a and c) …
Dna Methylation: Atherosclerosis Leading To Congenital Heart Diseases, Sher Khan, Rehana Rehman
Dna Methylation: Atherosclerosis Leading To Congenital Heart Diseases, Sher Khan, Rehana Rehman
Department of Biological & Biomedical Sciences
No abstract provided.