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Anatomical Analysis Of Olfactory Sensory Neuron Regeneration Via Glomerular Synaptic Activity Markers In Adult Mice, William Wamack
Anatomical Analysis Of Olfactory Sensory Neuron Regeneration Via Glomerular Synaptic Activity Markers In Adult Mice, William Wamack
Undergraduate Honors Theses
The olfactory system is a great model for studying regeneration due to the olfactory epithelium’s regenerative capability which makes it a potential a source of neural stem cells. The olfactory epithelium presents three types of cells: sustentacular cells which provide support and act as glial supporting cells; olfactory sensory neurons that are in charge of detecting odorant molecules in the air; and the stem cells that generated the aforementioned cell types. Olfactory sensory neurons are constantly dying and being replaced by new neurons originating from the stem cells that lie at the base of the olfactory epithelium. We have used …
The Effects Of Delta-9 Tetrahydrocannabinol (Thc) On Responding For Non-Drug Reinforcers In Rats., Anna Radford
The Effects Of Delta-9 Tetrahydrocannabinol (Thc) On Responding For Non-Drug Reinforcers In Rats., Anna Radford
Undergraduate Honors Theses
Although cannabis is widely consumed by humans for the intoxicating effects that are mediated by delta-9 tetrahydrocannabinol (THC), pre-clinical models of THC self-administration have been difficult to establish. We hypothesized that THC may have reinforcement enhancing effects comparable to other drugs (e.g., nicotine and caffeine), which are also widely consumed by humans but difficult to establish as primary reinforcers in non-human animals. To investigate whether THC is a reinforcement enhancer, male (M, n=8) and female (F, n=8) rats were shaped to self-administer a reinforcing saccharin (SACC) solution (0.2% w/v) in standard operant chambers equipped with infrared beams to monitor locomotor …