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Behavioral Neurobiology

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Doctoral Dissertations

Aromatase

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Full-Text Articles in Life Sciences

Acute Estrogen Synthesis And Action In The Auditory Cortex Of Developing Male Zebra Finches (Taeniopygia Guttata), Daniel Vahaba Jul 2019

Acute Estrogen Synthesis And Action In The Auditory Cortex Of Developing Male Zebra Finches (Taeniopygia Guttata), Daniel Vahaba

Doctoral Dissertations

Birdsong, as with human speech, is learned during an age- and experience-dependent sensitive period early in life. Songbirds must first memorize their parents’ song during a sensory phase, then refine their own burgeoning vocalizations to match the auditory memory of their parents’ song during a sensorimotor phase. While the error-correction aspect of the sensorimotor phase of song learning is comparatively well understood, it is largely unknown how auditory memories are formed and how auditory processing may change across development to facilitate song memorization. The songbird caudomedial nidopallium (NCM) is a brain region that encodes complex communication signals like song and …


The Cellular Context Of Estradiol Regulation In The Zebra Finch Auditory Forebrain, Maaya Ikeda Nov 2016

The Cellular Context Of Estradiol Regulation In The Zebra Finch Auditory Forebrain, Maaya Ikeda

Doctoral Dissertations

Estradiol, traditionally known as a hormone that communicates with distant cells in the body, is also synthesized locally in the brain to act as a neuromodulator. Neuromodulators differ from neurotransmitters in that they simultaneously affect a population of neurons and their actions are not limited to the synapse. One of the many effects of estradiol signaling is rapid modulation of auditory processing in response to external stimuli. The enzyme required for estradiol synthesis, aromatase, is highly expressed in the regions that are involved in higher-order processing of sounds in humans and songbirds. Since zebra finches, a type of songbird, are …