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The Determination Of Antibody Levels In Endodontic Patients Against Eleven Microorganisms Using Ifa And Elisa Techniques, William C. Payne
The Determination Of Antibody Levels In Endodontic Patients Against Eleven Microorganisms Using Ifa And Elisa Techniques, William C. Payne
Loma Linda University Electronic Theses, Dissertations & Projects
Endodontic (root canal) infections are generally considered to be caused by the invasion of microorganisms which destroy pulp tissue and extend to the periapical region. No definitive study has identified a specific bacterium or group of bacteria as etiological agents. We quantitively measured antibodies present in the serum of 30 normal individuals and patients with either chronic (n = 30) or acute (n = 30) periapical lesions with the indirect fluorescent antibody (IFA) and enzyme-linked immunosorbent assay (ELISA) for IgG and IgM against 11 oral microorganisms routinely isolated from such lesions. The results were analyzed statistically. Analysis of variance of …