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Histamine H1 Receptor Agonist And Control Of Olanzapine-Induced Obesity, Jiamei Lian, Xu-Feng Huang, N Pai, C Deng Sep 2012

Histamine H1 Receptor Agonist And Control Of Olanzapine-Induced Obesity, Jiamei Lian, Xu-Feng Huang, N Pai, C Deng

Xu-Feng Huang

No abstract provided.


Ventromedial Hypothalamic Npy Y2 Receptor In The Maintenance Of Body Weight In Diet-Induced Obesity In Mice, Yulin Li, Xu-Feng Huang, Chao Deng, Qing Wang, Timothy South, Yinghua Yu Sep 2012

Ventromedial Hypothalamic Npy Y2 Receptor In The Maintenance Of Body Weight In Diet-Induced Obesity In Mice, Yulin Li, Xu-Feng Huang, Chao Deng, Qing Wang, Timothy South, Yinghua Yu

Xu-Feng Huang

This study examined changes in neuropeptide Y (NPY) Y2 receptor binding in the brains of C57BL/6 mice in response to different levels of high-fat diets via three dietary intervention methods: high-fat diet, switching from high- to low-fat diet and finally, energy restricted high-fat diet. Forty-five C57Bl/6 male mice were fed a high-fat diet for 8 weeks and then classified as diet-induced obese (DIO) or diet-resistant (DR) mice according to the highest and lowest body weight gainers, respectively. The DIO and DR mice were then randomly divided into three groups each and either continued on their high-fat diet ad libitum (DIO-H …


A Link Between Chronic Sleep Restriction And Obesity: Methodological Considerations, Christopher Magee, Donald Iverson, Xu-Feng Huang, Peter Caputi Sep 2012

A Link Between Chronic Sleep Restriction And Obesity: Methodological Considerations, Christopher Magee, Donald Iverson, Xu-Feng Huang, Peter Caputi

Xu-Feng Huang

Emerging evidence suggests that chronicsleeprestriction contributes to obesity. Targeting short sleep duration may therefore offer a novel and effective method of preventing and treating obesity. However, this area of research is only in its infancy, and a complete understanding of how chronicsleeprestriction and obesity are linked is currently lacking. The aim of this paper is to briefly review epidemiological evidence for an association between chronicsleeprestriction and obesity in adults, and outline the key methodological limitations of these studies. Particular attention is paid to the methods used to measure sleep and obesity, as well as the need to control for potential …


Effects Of Diets High In Whey, Soy, Red Meat And Milk Protein On Body Weight Maintenance In Diet-Induced Obesity In Mice, Xu-Feng Huang, Y Liu, Gita Rahardjo, Peter Mclennan, Linda Tapsell, William Buttemer Sep 2012

Effects Of Diets High In Whey, Soy, Red Meat And Milk Protein On Body Weight Maintenance In Diet-Induced Obesity In Mice, Xu-Feng Huang, Y Liu, Gita Rahardjo, Peter Mclennan, Linda Tapsell, William Buttemer

Xu-Feng Huang

This study examined the effects of different food sources of protein on energy intake, body weight maintenance, and on the responses of plasma leptin, insulin and adiponectin in chronic high-fat diet-induced obese mice. Obesity was induced in 47 mice with a high-fat diet for 20 weeks. They were divided into five diet groups to test the effects of a higher protein proportion (30% energy), achieved at the expense of carbohydrate. For the next eight weeks, four of the groups were fed diets of chow formulated with whey, soy, red meat or milk while the control group continued on their high-fat …


Examining The Pathways Linking Chronic Sleep Restriction To Obesity, Christopher A. Magee, Xu-Feng Huang, Donald C. Iverson, Peter Caputi Sep 2012

Examining The Pathways Linking Chronic Sleep Restriction To Obesity, Christopher A. Magee, Xu-Feng Huang, Donald C. Iverson, Peter Caputi

Xu-Feng Huang

A growing number of studies have identified chronic sleep restriction as a potential risk factor for obesity. This could have important implications for how obesity is prevented and managed, but current understanding of the processes linking chronic sleep restriction to obesity is incomplete. In this paper, we examined some of the pathways that could underlie the relationship between chronic sleep restriction and obesity. This involved exploring some of the potential environmental, health, behavioral, and sociodemographic determinants of chronic sleep restriction, which require further investigation in this context. Three pathways that could potentially link chronic sleep restriction to obesity were then …


Temporal And Site-Specific Brain Alterations In Cb1 Receptor Binding In High Fat Diet-Induced Obesity In C57bl/6 Mice, Xu-Feng Huang, Timothy South Sep 2012

Temporal And Site-Specific Brain Alterations In Cb1 Receptor Binding In High Fat Diet-Induced Obesity In C57bl/6 Mice, Xu-Feng Huang, Timothy South

Xu-Feng Huang

The cannabinoid CB1 receptor has been implicated in the regulation of appetite and the consumption of palatable foods. This experiment aimed to explore the involvement of the CB1 receptor in the early and late stages of high fat diet-induced obesity in C57BL/6 mice. The C57Bl/6 mice were placed on a high fat (HF) or low fat/high carbohydrate (LF) diet for 3 or 20 weeks. Quantitative autoradiography revealed that binding of [3H] CP-55,940 (CB1 receptor ligand) was elevated following 3 weeks of HF feeding in areas including the medial/ventral anterior olfactory nucleus (22.1%), agranular insular cortex (24.0%) and the hypothalamus (31.5%) …


G Protein-Coupled Receptor 12 Deficiency Results In Decreased Energy Expenditure, Dyslipidemia And Obesity In Mice, L. Svensson, Xu-Feng Huang, M Jonnson, M Bjursell, M Boholooly, J Tornell, V Surve, A Gerdin Sep 2012

G Protein-Coupled Receptor 12 Deficiency Results In Decreased Energy Expenditure, Dyslipidemia And Obesity In Mice, L. Svensson, Xu-Feng Huang, M Jonnson, M Bjursell, M Boholooly, J Tornell, V Surve, A Gerdin

Xu-Feng Huang

No abstract provided.


Differential Expression Of Dopamine D2 And D4 Receptor And Tyrosine Hydroxylase Mrna In Mice Prone, Or Resistant, To Chronic High-Fat Diet-Induced Obesity, Xu-Feng Huang, Yinghua Yu, Katerina Zavitsanou, Mei Han, Leonard Storlien Sep 2012

Differential Expression Of Dopamine D2 And D4 Receptor And Tyrosine Hydroxylase Mrna In Mice Prone, Or Resistant, To Chronic High-Fat Diet-Induced Obesity, Xu-Feng Huang, Yinghua Yu, Katerina Zavitsanou, Mei Han, Leonard Storlien

Xu-Feng Huang

The present study examined brain dopamine D2 and D4 receptor and tyrosine hydroxylase (TH) mRNA expression in chronic high-fat diet-induced obese (cDIO) and obese-resistant (cDR) mice. Twenty-eight mice were fed a high-fat diet (HF: 40% of calories from fat) for 6 weeks and then classified as cDIO (n = 8) or cDR (n = 8) mice according to the highest and lowest body weight gainers, respectively. Seven mice were fed a low-fat diet (LF: 10% of calories from fat) and used as controls. After 20 weeks of feeding, visceral fat per gram of initial body weight was significantly higher in …


Diets High In Oat-Derived Beta-Glucan Promote Negative Energy Regulatory Pathway Of Hypothalamic Npy System In Chronic Diet-Induced Obesity In Mice, Xu-Feng Huang, Timothy South, Eleanor Beck, Marijka Batterham, K. Grinter, Linda Tapsell Sep 2012

Diets High In Oat-Derived Beta-Glucan Promote Negative Energy Regulatory Pathway Of Hypothalamic Npy System In Chronic Diet-Induced Obesity In Mice, Xu-Feng Huang, Timothy South, Eleanor Beck, Marijka Batterham, K. Grinter, Linda Tapsell

Xu-Feng Huang

No abstract provided.


Dopamine Transporter And D2 Receptor Densities In Mice Prone Or Resistant To Chronic High-Fat Diet-Induced Obesity, Xu-Feng Huang, F Chen, A Lawrence, Katerina Zavitsanou, Chao Deng, Hong-Qin Wang, Yinghua Yu Sep 2012

Dopamine Transporter And D2 Receptor Densities In Mice Prone Or Resistant To Chronic High-Fat Diet-Induced Obesity, Xu-Feng Huang, F Chen, A Lawrence, Katerina Zavitsanou, Chao Deng, Hong-Qin Wang, Yinghua Yu

Xu-Feng Huang

No abstract provided.


Fat In Food And The Obesity Epidemic, Linda C. Tapsell Jul 2012

Fat In Food And The Obesity Epidemic, Linda C. Tapsell

L. C. Tapsell

Dietary fat is strongly implicated in the development of insulin resistance and obesity, both major public health problems today. While the amount of dietary fat is relevant, the type of fat is important in fuel utilisation, storage and appetite regulatory mechanisms. Human calorimetry research confirms the importance of dietary fat in energy balance, but more work needs to be done to uncover the impact of type of dietary fat in weight control. Population and intervention research confirm the importance of fat in dietary interventions, bearing in mind the contribution of physical activity to energy balance. The food industry has an …


Is Sleep Duration Associated With Obesity In Older Australian Adults?, Christopher A. Magee, Peter Caputi, Don C. Iverson Jun 2012

Is Sleep Duration Associated With Obesity In Older Australian Adults?, Christopher A. Magee, Peter Caputi, Don C. Iverson

Don C. Iverson

Objectives: To investigate the relationship between sleep duration and obesity in older Australian adults. Method: Self-reported health data were collected through the 45 and Up Study. Multinomial logistic regression models were used to test the relationship between sleep duration and body mass index, controlling for a range of demographic and health-related variables. Results: The sample included 45,325 Australian adults aged 55 to 95 years. The regression models demonstrated that short and long sleep were associated with obesity in 55- to 64-year-olds but not in those aged 65 years and above. Discussion: The present results suggest that the relationships between sleep …


A Link Between Chronic Sleep Restriction And Obesity: Methodological Considerations, Christopher Magee, Donald Iverson, Xu-Feng Huang, Peter Caputi Jun 2012

A Link Between Chronic Sleep Restriction And Obesity: Methodological Considerations, Christopher Magee, Donald Iverson, Xu-Feng Huang, Peter Caputi

Don C. Iverson

Emerging evidence suggests that chronicsleeprestriction contributes to obesity. Targeting short sleep duration may therefore offer a novel and effective method of preventing and treating obesity. However, this area of research is only in its infancy, and a complete understanding of how chronicsleeprestriction and obesity are linked is currently lacking. The aim of this paper is to briefly review epidemiological evidence for an association between chronicsleeprestriction and obesity in adults, and outline the key methodological limitations of these studies. Particular attention is paid to the methods used to measure sleep and obesity, as well as the need to control for potential …


Sleep Duration And Obesity In Middle-Aged Australian Adults, Christopher A. Magee, Donald C. Iverson, Peter Caputi Jun 2012

Sleep Duration And Obesity In Middle-Aged Australian Adults, Christopher A. Magee, Donald C. Iverson, Peter Caputi

Don C. Iverson

The present study examined the association between sleep duration and obesity in 40,834 middle-aged Australian adults. Multinomial logistic regression was used to test the relationship between sleep duration and obesity while controlling for important demographic and health covariates; separate models were tested for males and females. Short sleep (i.e., <7 h a night) was found to be independently associated with obesity in males and females. To our knowledge, this is the first study to report an association between short sleep and obesity in Australian adults. Although more research is required, interventions targeting short sleep could aid obesity treatment and prevention.


Family Practice Residents' Identification And Management Of Obesity, R Mcartor, Donald Iverson, D Benken, L Dennis Jun 2012

Family Practice Residents' Identification And Management Of Obesity, R Mcartor, Donald Iverson, D Benken, L Dennis

Don C. Iverson

This study, involving 25 family practice residents and 2746 patients in a family practice residency programme, addressed four hypotheses regarding the identification and management of obesity in the primary care setting: (i) the physician-identified prevalence of obesity is significantly lower than the actual prevalence in the population, (ii) obesity is more likely to be addressed with management actions when it is recorded on the medical record problem list than when it is not recorded, (iii) physician actions dealing with obesity are influenced by the patient's age, sex, level of motivation, and body mass index (BMI) value, and (iv) the type …


Examining The Pathways Linking Chronic Sleep Restriction To Obesity, Christopher A. Magee, Xu-Feng Huang, Donald C. Iverson, Peter Caputi Jun 2012

Examining The Pathways Linking Chronic Sleep Restriction To Obesity, Christopher A. Magee, Xu-Feng Huang, Donald C. Iverson, Peter Caputi

Don C. Iverson

A growing number of studies have identified chronic sleep restriction as a potential risk factor for obesity. This could have important implications for how obesity is prevented and managed, but current understanding of the processes linking chronic sleep restriction to obesity is incomplete. In this paper, we examined some of the pathways that could underlie the relationship between chronic sleep restriction and obesity. This involved exploring some of the potential environmental, health, behavioral, and sociodemographic determinants of chronic sleep restriction, which require further investigation in this context. Three pathways that could potentially link chronic sleep restriction to obesity were then …


The Change Program: Comparing An Interactive Versus Prescriptive Obesity Intervention On University Students' Self-Esteem And Functional Health Status, Erin Pearson, Jennifer Irwin, Don Morrow Dec 2011

The Change Program: Comparing An Interactive Versus Prescriptive Obesity Intervention On University Students' Self-Esteem And Functional Health Status, Erin Pearson, Jennifer Irwin, Don Morrow

Donald Morrow

Background: Previous studies incorporating Motivational Interviewing administered via Co‐Active Life Coaching tools (MI‐via‐CALC) have elicited positive results among adults with obesity. However, there is a paucity of this research that includes sufficient power and a comparison group. This study's purpose was to compare MI‐via‐CALC with a validated obesity intervention among university students. Methods: Participants (n = 45) were randomised to either a telephone‐based 12‐week: (a) MI‐via‐CALC program whereby a certified coach worked with subjects to achieve goals through dialogue; or (b) lifestyle modification treatment following the LEARN Program for Weight Management. Participants completed the Rosenberg Self‐Esteem Scale and Short Form …


The Change Program: Comparing An Interactive Versus Prescriptive Obesity Intervention On University Students’ Self-Esteem And Quality Of Life, Don Morrow, Erin Pearson, Jennifer Irwin, Hall Craig Dec 2011

The Change Program: Comparing An Interactive Versus Prescriptive Obesity Intervention On University Students’ Self-Esteem And Quality Of Life, Don Morrow, Erin Pearson, Jennifer Irwin, Hall Craig

Donald Morrow

Previous studies incorporating Motivational Interviewing administered via Co-Active Life Coaching tools (MI-via-CALC) have elicited positive results among adults with obesity. However, there is a paucity of this research that includes sufficient power and a comparison group. This study’s purpose was to compare MI-via-CALC with a validated obesity intervention among university students. Methods: Participants (n = 45) were randomised to either a telephone-based 12-week: (a) MI-via-CALC program whereby a certified coach worked with subjects to achieve goals through dialogue; or (b) lifestyle modification treatment following the LEARN Program for Weight Management. Participants completed the Rosenberg Self-Esteem Scale and Short Form Functional …