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Full-Text Articles in Life Sciences
Nutrient Loading And Eutrophication In The Great Salt Lake, Wayne A. Wurtsbaugh
Nutrient Loading And Eutrophication In The Great Salt Lake, Wayne A. Wurtsbaugh
Watershed Sciences Faculty Publications
No abstract provided.
Genomic Profiling Reveals An Alternate Mechanism For Hepatic Tumor Promotion By Perfluorooctanoic Acid In Rainbow Trout, Susan C. Tilton, Gayle A. Orner, Abby D. Benninghoff, Hillary M. Carpenter, Jerry D. Hendricks, Cliff B. Pereira, David E. Williams
Genomic Profiling Reveals An Alternate Mechanism For Hepatic Tumor Promotion By Perfluorooctanoic Acid In Rainbow Trout, Susan C. Tilton, Gayle A. Orner, Abby D. Benninghoff, Hillary M. Carpenter, Jerry D. Hendricks, Cliff B. Pereira, David E. Williams
Animal, Dairy, and Veterinary Science Faculty Publications
Background
Perfluorooctanoic acid (PFOA) is a potent hepatocarcinogen and peroxisome proliferator (PP) in rodents. Humans are not susceptible to peroxisome proliferation and are considered refractory to carcinogenesis by PPs. Previous studies with rainbow trout indicate they are also insensitive to peroxisome proliferation by the PP dehydroepiandrosterone (DHEA), but are still susceptible to enhanced hepatocarcinogenesis after chronic exposure.
Objectives
In this study, we used trout as a unique in vivo tumor model to study the potential for PFOA carcinogenesis in the absence of peroxisome proliferation compared with the structurally diverse PPs clofibrate (CLOF) and DHEA. Mechanisms of carcinogenesis were identified from …
Lakes And Forests As Determinants Of Downstream Nutrient Concentrations In Small Mountain Watersheds, P. D. Brown, Wayne A. Wurtsbaugh, K. Nydick
Lakes And Forests As Determinants Of Downstream Nutrient Concentrations In Small Mountain Watersheds, P. D. Brown, Wayne A. Wurtsbaugh, K. Nydick
Watershed Sciences Faculty Publications
Lakes are dynamic processors of nutrients and may hold an active role in modifying the water chemistry of stream systems. In this study, we examine the influence of lakes and an important terrestrial component—forest cover—on the nutrient levels of stream water in 11 Rocky Mountain (Idaho) watersheds. Water samples were collected from the inflow and outflow of lakes with varying amounts of upstream lakes and forested area during spring runoff and summer base flow. During base flow, mean total nitrogen concentrations at the inflow of final lakes were significantly related to relative upstream lake area, increasing from 34 to 103 …