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Full-Text Articles in Life Sciences
Modeling Vascular Diffusion Of Oxygen In Breast Cancer, Tina Giorgadze
Modeling Vascular Diffusion Of Oxygen In Breast Cancer, Tina Giorgadze
Senior Projects Spring 2023
Oxygen is a vital nutrient necessary for tumor cells to survive and proliferate. Oxygen is diffused from our blood vessels into the tissue, where it is consumed by our cells. This process can be modeled by partial differential equations with sinks and sources. This project focuses on adding an oxygen diffusion module to an existing 3D agent-based model of breast cancer developed in Dr. Norton’s lab. The mathematical diffusion module added to an existing agent-based model (ABM) includes deriving the 1-dimensional and multi-dimensional diffusion equations, implementing 2D and 3D oxygen diffusion models into the ABM, and numerically evaluating those equations …
Mathematical Modeling Suggests Cooperation Of Plant-Infecting Viruses, Joshua Miller, Vitaly V. Ganusov, Tessa Burch-Smith
Mathematical Modeling Suggests Cooperation Of Plant-Infecting Viruses, Joshua Miller, Vitaly V. Ganusov, Tessa Burch-Smith
Chancellor’s Honors Program Projects
No abstract provided.
Analytic Solutions For Diffusion On Path Graphs And Its Application To The Modeling Of The Evolution Of Electrically Indiscernible Conformational States Of Lysenin, K. Summer Ware
Boise State University Theses and Dissertations
Memory is traditionally thought of as a biological function of the brain. In recent years, however, researchers have found that some stimuli-responsive molecules exhibit memory-like behavior manifested as history-dependent hysteresis in response to external excitations. One example is lysenin, a pore-forming toxin found naturally in the coelomic fluid of the common earthworm Eisenia fetida. When reconstituted into a bilayer lipid membrane, this unassuming toxin undergoes conformational changes in response to applied voltages. However, lysenin is able to "remember" past history by adjusting its conformational state based not only on the amplitude of the stimulus but also on its previous …
Upper, Lower Solutions And Analytic Semigroups For A Model With Diffusion, Yannick T. Kouakep
Upper, Lower Solutions And Analytic Semigroups For A Model With Diffusion, Yannick T. Kouakep
Applications and Applied Mathematics: An International Journal (AAM)
In this discussion we consider an autonomous parabolic epidemic 2-dimensional system modelling the dynamics of transmission of immunizing diseases for a closed population into bounded regular domain. Our model takes into account diffusion of population with external influx as well as one class of infected individuals. We study the well-posedness two-component diffusion equations including external supplies with Neumann conditions using upper/lower solutions and analytic semigroups. In case of constant population or not, with non-oscillatory solution and constant diffusion, this problem admits travelling wave solutions whose minimum wave speed is surveyed here.
Nonlinear Dynamics Of Filaments In Free Space And Fluids, Victoria Kelley
Nonlinear Dynamics Of Filaments In Free Space And Fluids, Victoria Kelley
Senior Honors Projects, 2010-2019
The purpose of this paper is to study a straight rod, held at both ends, with a known twist and tension or compression. We study the stability of this steady state when the system is dominated either by inertia or drag. In order to do this, we first replicate the work of Goriely and Tabor to look at the case with inertia, without drag. After conducting the analysis for that case, we then apply their framework to perform a linear stability analysis of a model that is without inertia, but with hydrodynamic drag. Our motivation is the study of locomotion …
Interdisciplinary Modeling For Water-Related Issues Graduate Course, Laurel Saito, Alexander Fernald, Timothy Link
Interdisciplinary Modeling For Water-Related Issues Graduate Course, Laurel Saito, Alexander Fernald, Timothy Link
All ECSTATIC Materials
The science and management of aquatic ecosystems is inherently interdisciplinary, with issues associated with hydrology, atmospheric science, water quality, geochemistry, sociology, economics, environmental science, and ecology. Addressing water resources issues in any one discipline invariably involves effects that concern other disciplines, and attempts to address one issue often have consequences that exacerbate existing issues or concerns, or create new ones (Jørgensen et al. 1992; Lackey et al. 1975; Straskraba 1994) due to the strongly interactive nature of key processes (Christensen et al. 1996). Thus, research and management of aquatic ecosystems must be interdisciplinary to be most effective, but such truly …
An Individual-Based Model Of Chaparral Vegetation Response To Frequent Wildfire, Timothy Lucas, Dayna Mann, Reanna Dona
An Individual-Based Model Of Chaparral Vegetation Response To Frequent Wildfire, Timothy Lucas, Dayna Mann, Reanna Dona
Seaver College Research And Scholarly Achievement Symposium
In recent years, the Santa Monica Mountains (SMM) have been plagued by frequent wildfires which threaten the native chaparral species. Nonsprouting chaparral species are completely killed by a fire, but their seeds germinate in response to fire cues. Facultative sprouters both resprout after a wildfire and release seeds that germinate post-fire. This project is based on data collected since 1986 at a biological preserve adjacent to the Malibu campus of Pepperdine University with an average fire return interval of 7.5 years. We present a spatial model that simulates the growth, seed dispersal and resprouting behavior of individual shrubs that compete …
Numerical Algorithms For Solving A Generalized Cancer Chemotherapy Problem, Frank Nani, Mingxian Jin
Numerical Algorithms For Solving A Generalized Cancer Chemotherapy Problem, Frank Nani, Mingxian Jin
Math and Computer Science Faculty Working Papers
In this paper, two elaborate numerical algorithms are presented for solving the Nani- Oguztoreli functional differential equations associated with cell-cycle specific cancer chemotherapy. The generalized cell-cycle specific cancer chemotherapy model of Nani- Oguztoreli contains discrete time delays which represent the times that the cancer cells spend in each cell-cycle phase. The model also takes into account that inter-cell cycle phase transition rate constants, recruitment of resting cells from the GO phase, and effect of chemotherapy drug on cells in each phase. The algorithms utilize a modified version of the Method of Steps algorithms. The constructed numerical schemes can be implemented …