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Microarray Analysis Reveals Distinctive Signaling Between The Bed Nucleus Of The Stria Terminalis, Nucleus Accumbens, And Dorsal Striatum, Christopher M. Olsen, Yong Pandey, Shirlean Goodwin, Daniel C. Ciobanu, Lu Lu, Thomas R. Sutter, Danny G. Winder
Microarray Analysis Reveals Distinctive Signaling Between The Bed Nucleus Of The Stria Terminalis, Nucleus Accumbens, And Dorsal Striatum, Christopher M. Olsen, Yong Pandey, Shirlean Goodwin, Daniel C. Ciobanu, Lu Lu, Thomas R. Sutter, Danny G. Winder
Department of Animal Science: Faculty Publications
Microarray analysis reveals distinctive signaling between the bed nucleus of the stria terminalis, nucleus accumbens, and dorsal striatum. Physiol Genomics 32: 283–298, 2008. First published October 2, 2006; doi:10.1152/physiolgenomics.00224.2006.—To identify distinct transcriptional patterns between the major subcortical dopamine targets commonly studied in addiction we studied differences in gene expression between the bed nucleus of the stria terminalis (BNST), nucleus accumbens (NAc), and dorsal striatum (dStr) using microarray analysis. We first tested for differences in expression of genes encoding transcripts for common neurotransmitter systems as well as calcium binding proteins routinely used in neuroanatomical delineation of brain regions. This a priori …