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Full-Text Articles in Life Sciences

Lymphocyte Proteomics For Monitoring Long Term Immune System Dynamics, Michaela Mccown Mar 2021

Lymphocyte Proteomics For Monitoring Long Term Immune System Dynamics, Michaela Mccown

Undergraduate Honors Theses

Time dependent change in lymphocytes provides a necessary background for monitoring the development of Chronic Lymphocytic Leukemia from asymptomatic to malignant. Several bulk proteomics studies characterize differences between tumor cells and healthy B cells, yet the transition to symptomatic disease is not well understood. This could be shown by a longitudinal study beginning with asymptomatic patients if the rare tumor cells in early stages can be isolated from small volume blood draws and effectively characterized with few cells, such as was done here using healthy B cells to provide a baseline for such studies to discriminate routine fluctuation from pathogenic …


Human Health And Economic Costs Of Air Pollution In Utah: An Expert Assessment, Isabella Errigo Aug 2020

Human Health And Economic Costs Of Air Pollution In Utah: An Expert Assessment, Isabella Errigo

Undergraduate Honors Theses

Recent scholarship has found that air pollution damages our health and economy more than previously understood, with approximately one in four deaths associated with exposure to air pollution globally. However, translating these research findings into policy and behavior change at local levels remains a major challenge, partially because of mismatch between the scale of air pollution research (often national or global) and governance frameworks (typically local to regional). Here, we used an expert assessment to bridge this research-policy divide in Utah, USA. We combined quantitative and qualitative input from 23 Utah-specific researchers and specialists, asking for estimates of human health …