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Full-Text Articles in Life Sciences
Identification Of Substrate-Selective Histone Deacetylases And Their Inhibitors That Mediate Her2 Transcript Stability, Mariah Alejo
Identification Of Substrate-Selective Histone Deacetylases And Their Inhibitors That Mediate Her2 Transcript Stability, Mariah Alejo
Dissertations, Masters Theses, Capstones, and Culminating Projects
Breast cancer is the most common malignancy diagnosed in women. 15-20% of these cancers overexpress the HER2 (ERRB2) oncoprotein. HER2-positive breast cancers are generally aggressive and are associated with poor prognosis. Unfortunately, only a mere 30% of HER2-positve patients respond to therapies when they are used as a single agent. Combining therapeutics can potentially lead to synergy and improved anticancer efficacy, and there is clearly a need for the development of new HER2-directed therapeutics. Newer approaches include the utilization of histone deacetylase (HDAC) inhibitors. It has been observed that HDAC inhibitors can induce the rapid decay of oncogenic transcripts such …
Stress Reducing Effects Of Indoor Plants In A Classroom Setting, Laura Tennant
Stress Reducing Effects Of Indoor Plants In A Classroom Setting, Laura Tennant
Student Research Posters
Previous research has demonstrated that natural views and access to plants appear to have significant beneficial effects on individuals (Relf, 1992). Studies of green views out of a classroom window showed significant reductions in students’ mental fatigue (Li & Sullivan, 2016), and studies of indoor plants in hospital settings showed stress reduction and increased healing rates in patients (Ulrich, 1984). Indoor plants in the workplace demonstrated improved employee performance (Kweon, Ulrich, Walker, & Tassinary, 2008). However, there have been few studies examining the impact indoor plants might have in a classroom setting. This study used an experimental design to measure …