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Full-Text Articles in Life Sciences
Adipogenic And Myogenic Stem Cells In Brown Fat: A Study Of Progenitors And Regenerative Capacity, Xin Yang
Adipogenic And Myogenic Stem Cells In Brown Fat: A Study Of Progenitors And Regenerative Capacity, Xin Yang
Open Access Theses
Brown adipose tissue (BAT) utilizes stored lipids to generate heat, therefore reducing body fat content and favoring a leaner body composition. Recent identification of metabolically active BAT in adult humans has sparked broad interests in understanding the developmental origin and postnatal homeostasis of BAT. However, the stem cell population that gives rise to BAT during development and maintains BAT mass at postnatal stage has not been characterized. In addition, whether adult BAT has the capacity to regenerate after injury or to proliferate in response to cold is flargely unknown. Furthermore, although BAT and skeletal muscle are known to share a …
Prediction Of Parturition And Dystocia In Holstein-Friesian Cattle, And Cesarean Section In Dystocic Beef Cattle, Wen Han Mark Hiew
Prediction Of Parturition And Dystocia In Holstein-Friesian Cattle, And Cesarean Section In Dystocic Beef Cattle, Wen Han Mark Hiew
Open Access Dissertations
Dystocia is a major problem in the dairy industry as it causes livestock and economic loss. It is more frequently seen in primiparous cattle compared to their multiparous counterparts due to their smaller stature and the slow maturation of pelvic dimensions. In some instances, human intervention of the parturition process is imperative to avoid pain, injury, and mortality of the neonate and the dam. The ability to accurately predict dystocia and the time of parturition will ensure that timely assistance can be given to animals that are of high risk of dystocia.^ The present thesis contains four studies that explore …
Cellular And Molecular Regulation Of Skeletal Muscle Regeneration, Chunhui Jiang
Cellular And Molecular Regulation Of Skeletal Muscle Regeneration, Chunhui Jiang
Open Access Dissertations
Skeletal muscle regeneration provides a powerful model to study the cellular and molecular mechanism governing stem cell function since the whole process is mediated by a population of muscle-resident stem cells called satellite cells. The overall aim of this dissertation is to explore the roles of Notch signaling and a novel gene (Bex1) in satellite cell function and skeletal muscle regeneration. ^ The first part of this thesis is to examine how the Notch signaling pathway regulates the satellite cell self-renewal in a disease model. The MDX mouse is a well-established model for Duchenne muscular dystrophy (DMD) and characterized by …
Karyopherin Alpha Subtypes And Porcine Early Stage Embryo Development, Yanfang Li
Karyopherin Alpha Subtypes And Porcine Early Stage Embryo Development, Yanfang Li
Open Access Dissertations
Intracellular communication between the nucleus and cytoplasm is critically important for coordinating cellular events during embryogenesis. The karyopherin α/β heterodimer is an intracellular nuclear trafficking system that mediates nuclear import of proteins that bear classical nuclear localization signals (NLSs). Seven karyopherin α subtypes have been identified in the domestic pig, and while each of these karyopherin α subtypes is able to bind to a nuclear localization signal, individual karyopherin α subtypes have been shown to transport specific NLS-bearing proteins. The objective of this study was to determine the developmental requirements of karyopherin α subtypes (KPNAs) during cleavage development in porcine …
The Effectiveness Of Virtual And On-Site Dairy Farm Field Trips To Increase Student Knowledge In Science, Social Studies, And Health And Wellness Standards, Abby M. Sweet
Open Access Theses
The integration of agriculture into the curriculum can be difficult for educators when materials and resources are not aligned with state learning standards. However, online educational tools, such as virtual field trips that are aligned with state learning standards, can allow for educators to bring the experience of a field trip to the classroom, as well as complement curriculum in the classroom. Virtual field trips also assist with removing many barriers that prevent educators from taking their students on an on-site field trip. ^ This study sought to describe the effectiveness of a virtual and on-site dairy farm field trip …