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Engineering Commons

Open Access. Powered by Scholars. Published by Universities.®

2019

Theses/Dissertations

The University of Akron

Biomedical Engineering and Bioengineering

MACF

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Full-Text Articles in Engineering

The Production And Characterization Of Chitosan Based Microgels Using A Novel Microfluidic Device To Promote Cell Survival, Kaileen Shevchuk Jan 2019

The Production And Characterization Of Chitosan Based Microgels Using A Novel Microfluidic Device To Promote Cell Survival, Kaileen Shevchuk

Williams Honors College, Honors Research Projects

The purpose of this project is to synthesize and characterize perfluorocarbon modified methacrylamide chitosan (MACF) microgels produced with the use of a capillary-based microfluidic device. Since cell survival and development is highly related to particles physical properties, analysis of microgels set out to determine the particle’s physical properties. I hypothesize that the viscosity of the MACF polymer as well as the amount of photo initiator influence the physical properties of synthesized particles and as a result can generate particles with various features for cell culture in terms of shape, size, charge and swelling abilities. This hypothesis was validated through the …