Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Engineering
Effects Of Nutrient Level And Growth Rate On Mutation And Conjugation Processes That Confer Antibiotic Resistance To E. Coli, Mohammadreza Shafieifini
Effects Of Nutrient Level And Growth Rate On Mutation And Conjugation Processes That Confer Antibiotic Resistance To E. Coli, Mohammadreza Shafieifini
Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research
Antibiotic resistance genes (ARGs) may enter surface water with the discharge of treated wastewater. Conjugation is a main mechanism for the horizontal gene transfer of ARGs from wastewater microbiome to the microbiome indigenous to surface water. However, little is known about how environmental factors affect the conjugation process of ARGs.
In this thesis, an extensive research related to spreading antibiotic resistance genes in the environment is reported. The project investigated how environmental parameters may affect the rate of dissemination of ARGs and in what extent the resistance level of the population is changed after mutation and conjugation event. The chemostat …