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Engineering Commons

Open Access. Powered by Scholars. Published by Universities.®

2019

Chemical Engineering

Theses/Dissertations

University of Louisville

Blood residence time

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Full-Text Articles in Engineering

Non-Invasive Detection And Assessment Of Coronary Stenosis From Blood Mean Residence Times., Javad Hashemi Dec 2019

Non-Invasive Detection And Assessment Of Coronary Stenosis From Blood Mean Residence Times., Javad Hashemi

Electronic Theses and Dissertations

Coronary artery stenosis is an abnormal narrowing of a coronary artery caused by an atherosclerotic lesion that reduces lumen space. Fractional flow reserve (FFR) is the gold standard method to determine the severity of coronary stenosis based on the determination of rest and hyperemic pressure fields, but requires an invasive medical procedure. Normal FFR is 1.0 and FFR RT, to account for varying volume and flow rate of individual segments. BloodRT was computed in 100 patients who had undergone the pressure-wire FFR procedure, and a threshold for BloodRT was determined to assess the physiological significance of a stenosis, …