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Articles 1 - 4 of 4
Full-Text Articles in Engineering
Review Of Methods For Intraoperative Margin Detection For Breast Conserving Surgery, Benjamin W. Maloney, David M. Mcclatchy, Brian W. Pogue, Keith D. Paulsen, Wendy A. Wells, Richard J. Barth
Review Of Methods For Intraoperative Margin Detection For Breast Conserving Surgery, Benjamin W. Maloney, David M. Mcclatchy, Brian W. Pogue, Keith D. Paulsen, Wendy A. Wells, Richard J. Barth
Dartmouth Scholarship
Breast conserving surgery (BCS) is an effective treatment for early-stage cancers as long as the margins of the resected tissue are free of disease according to consensus guidelines for patient management. However, 15% to 35% of patients undergo a second surgery since malignant cells are found close to or at the margins of the original resection specimen. This review highlights imaging approaches being investigated to reduce the rate of positive margins, and they are reviewed with the assumption that a new system would need high sensitivity near 95% and specificity near 85%. The problem appears to be twofold. The first …
Tissue Oxygen Saturation Predicts Response To Breast Cancer Neoadjuvant Chemotherapy Within 10 Days Of Treatment, Jeffrey M. Cochran, David R. Busch, Anais Leproux, Zheng Zhang, Thomas D. O'Sullivan, Albert E. Cerussi, Philip M. Carpenter, Rita S. Mehta, Darren Roblyer, Wei Yang, Keith D. Paulsen, Brian Pogue, Shudong Jiang, Peter A. Kaufman
Tissue Oxygen Saturation Predicts Response To Breast Cancer Neoadjuvant Chemotherapy Within 10 Days Of Treatment, Jeffrey M. Cochran, David R. Busch, Anais Leproux, Zheng Zhang, Thomas D. O'Sullivan, Albert E. Cerussi, Philip M. Carpenter, Rita S. Mehta, Darren Roblyer, Wei Yang, Keith D. Paulsen, Brian Pogue, Shudong Jiang, Peter A. Kaufman
Dartmouth Scholarship
Ideally, neoadjuvant chemotherapy (NAC) assessment should predict pathologic complete response (pCR), a surrogate clinical endpoint for 5-year survival, as early as possible during typical 3- to 6-month breast cancer treatments. We introduce and demonstrate an approach for predicting pCR within 10 days of initiating NAC. The method uses a bedside diffuse optical spectroscopic imaging (DOSI) technology and logistic regression modeling. Tumor and normal tissue physiological properties were measured longitudinally throughout the course of NAC in 33 patients enrolled in the American College of Radiology Imaging Network multicenter breast cancer DOSI trial (ACRIN-6691). An image analysis scheme, employing z-score normalization to …
A Simple Method Of Coil Design, M. Rawlik, A. Eggenberger, J. Krempel, Christopher Crawford, K. Kirch, F. M. Piegsa, G. Quéméner
A Simple Method Of Coil Design, M. Rawlik, A. Eggenberger, J. Krempel, Christopher Crawford, K. Kirch, F. M. Piegsa, G. Quéméner
Physics and Astronomy Faculty Publications
In this article, we present a method to design a coil producing an arbitrarily shaped magnetic field by restricting the path of the coil's wires to a regular grid. The solution is then found by a simple least squares minimum. We discuss practical applications, in particular, in the active magnetic field stabilization system of the neutron electric dipole moment experiment at the Paul Scherrer Institute in Villigen, Switzerland. We also publish the software implementation of the method.
Estimating Left Ventricular Volume With Roi-Based Convolutional Neural Network, Feng Zhu
Estimating Left Ventricular Volume With Roi-Based Convolutional Neural Network, Feng Zhu
Turkish Journal of Electrical Engineering and Computer Sciences
The volume of the human left ventricular (LV) chamber is an important indicator for diagnosing heart disease. Although LV volume can be measured manually with cardiac magnetic resonance imaging (MRI), the process is difficult and time-consuming for experienced cardiologists. This paper presents an end-to-end segmentation-free method that estimates LV volume from MRI images directly. The method initially uses Fourier transform and a regression filter to calculate the region of interest that contains the LV chambers. Then convolutional neural networks are trained to estimate the end-diastolic volume (EDV) and end-systolic volume (ESV). The resulting models accurately estimate the EDV and ESV …