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Developing Photoacoustic Tomography Devices For Translational Medicine And Basic Science Research, Tsz Wai Wong
Developing Photoacoustic Tomography Devices For Translational Medicine And Basic Science Research, Tsz Wai Wong
McKelvey School of Engineering Theses & Dissertations
Photoacoustic (PA) tomography (PAT) provides volumetric images of biological tissue with scalable spatial resolutions and imaging depths, while preserving the same imaging contrast—optical absorption. Taking the advantage of its 100% sensitivity to optical absorption, PAT has been widely applied in structural, functional, and molecular imaging, with both endogenous and exogenous contrasts, at superior depths than pure optical methods. Intuitively, hemoglobin has been the most commonly studied biomolecule in PAT due to its strong absorption in the visible wavelength regime.
One of the main focuses of this dissertation is to investigate an underexplored wavelength regime—ultraviolet (UV), which allows us to image …