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Full-Text Articles in Engineering

A Genetic Algorithm For Asic Floorplanning, Anvesh Kumar Perumalla Jan 2016

A Genetic Algorithm For Asic Floorplanning, Anvesh Kumar Perumalla

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Semiconductor integrated circuits (ICs) have become key components in almost every aspect of our daily lives. From simple home appliances to extremely sophisticated aerospace systems, we have become increasingly dependent on ICs. System-on-chip (SoC) is an IC methodology that includes multiple design technologies on a single IC chip. SoC was developed to further integrate and manage system complexity. Due to SoC and increasingly dense IC fabrication technologies, design time and thereby system time-to-market are becoming more critical drivers of the IC design cycle. In order to address issues related to design time and time-to-market, highly optimized semiconductor intellectual property (IP) …


Dynamic Level-2 Cache Memory Locking By Utilizing Multiple Miss Tables, Andrew Louis Mocniak Jan 2016

Dynamic Level-2 Cache Memory Locking By Utilizing Multiple Miss Tables, Andrew Louis Mocniak

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Cache memory plays a vital role in a system's performance by acting as a buffer to quickly supply requested instruction/data blocks from the main memory to the central processing unit (CPU). Cache management techniques may increase or decrease a system's performance. The results vary from process to process, depending on how well optimized the cache management technique is for a particular process. The inclusion of level-2 (L2) cache locking has been shown in previous studies to be beneficial in increasing a system's performance. This is further improved upon through the inclusion of a miss table (MT), which keeps track of …


Accelerated Hyperspectral Unmixing With Endmember Variability Via The Sum-Product Algorithm, Charan Puladas Jan 2016

Accelerated Hyperspectral Unmixing With Endmember Variability Via The Sum-Product Algorithm, Charan Puladas

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The rich spectral information captured by hyperspectral sensors has given rise to a number of remote sensing applications, ranging from vegetative assessment and crop health monitoring, to military surveillance and combatant identification. However, due to limited spatial resolution, multiple ground materials generally contribute, i.e. mix, to form the spectrum recorded for a single pixel. The unmixing problem considers the inverse problem of determining the underlying material spectra, called endmembers, from sensor measurements. While classical unmixing approaches were deterministic in nature and did not attempt to identify in-scene materials, recent methods use labeled training data to generate statistical models of endmember …


The Effect Of Laser Power And Scan Speed On Melt Pool Characteristics Of Pure Titanium And Ti-6al-4v Alloy For Selective Laser Melting, Chandrakanth Kusuma Jan 2016

The Effect Of Laser Power And Scan Speed On Melt Pool Characteristics Of Pure Titanium And Ti-6al-4v Alloy For Selective Laser Melting, Chandrakanth Kusuma

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Selective Laser Melting (SLM) is an additive manufacturing (AM) technique that creates complex parts by selectively melting metal powder layer-by-layer. In SLM, the process parameters decide the quality of the fabricated component. In this study, single beads of commercially pure titanium (CP-Ti) and Ti-6Al-4V alloy are melted on a substrate of the same material as powder using an in-house built SLM machine. Multiple combinations of laser power and scan speed are used for single bead fabrication while the laser beam diameter and powder layer thickness are kept constant. This experimental study investigates the influence of laser power, scan speed and …


Characterization Of Peripheral Lung Lesions By Statistical Image Processing Of Endobronchial Ultrasound Images, Aaron T. Madaris Jan 2016

Characterization Of Peripheral Lung Lesions By Statistical Image Processing Of Endobronchial Ultrasound Images, Aaron T. Madaris

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This thesis introduces the concept of implementing greyscale analysis, also known as intensity analysis, on endobronchial ultrasound (EBUS) images for the purposes of diagnosing peripheral lung tumors. The statistical methodology of using greyscale and histogram analysis allows the characterization of lung tissue in EBUS images. Regions of interest (ROI) will be analyzed in MATLAB and a feature vector will be created. A feature vector of first-order, second-order and histogram greyscale analysis will be created and used for the classification of malignant vs benign peripheral lung tumors. The tools that were implemented were MedCalc for the initial statistical analysis of receiver …


Mixed Modulation For Remote Sensing With Embedded Navigation, Michael J. Nowak Jan 2016

Mixed Modulation For Remote Sensing With Embedded Navigation, Michael J. Nowak

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As electromagnetic spectrum availability shrinks, there is growing interest in combining multiple functions, such as radar and communications signals, into a single multipurpose waveform. Historically mixed-modulation has used orthogonal separation of different message signals in different dimensions such as time or frequency. This research explores an alternative approach of implementing an in-band, mixed-modulated waveform that combines surveillance radar and navigation functions into a single signal and demonstrates the feasibility of this approach for a limited area navigation solution. The first contribution of this research is the use of reduced phase-angle binary phase shift keying (BPSK) along with overlapped (channelized) spread-spectrum …


Retail Facility Design Considering Product Exposure, Corinne H. Mowrey Jan 2016

Retail Facility Design Considering Product Exposure, Corinne H. Mowrey

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Retail store's layout affects a shopper's visual experience and correspondingly the time spent in the store, navigation through the aisles, and allocation of attention and money across departments and categories. We contend that alternate rack layouts allow for more of a rack's facing to appear in the shopper's visual field. In this work we focus on the following two questions: (i) what impact does a given rack layout have on how much of a rack display is exposed to a shopper? (ii) what rack layouts maximize exposure to a shopper? To address the first question, we introduce a set of …


Evaluation Of Real-Time Adaptive Display Systems In A Pilot Training Environment, Jerred Charles Holt Jan 2016

Evaluation Of Real-Time Adaptive Display Systems In A Pilot Training Environment, Jerred Charles Holt

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The Air Force (AF) has traditionally utilized a frequency-based approach that relies on after-action review for feedback to train their pilots. The goal of this study is to evaluate the effectiveness of adding real-time adaptive supplemental feedback to this approach. A synthetic task environment was developed to emulate the current AF training platform. Supplemental HUD displays were developed that captured various degrees of expertise at the flight task, thereby serving as a both training and performance aids. Varied presentation schedules for these supplemental displays and triggers for their dynamic behavior were compared and evaluated based on performance, knowledge and workload …


Novel Therapeutic Approach For Regulating The Susceptibility Of Epitheliato Adenovirus Infection, Mahmoud Soliman Salem Alghamri Jan 2016

Novel Therapeutic Approach For Regulating The Susceptibility Of Epitheliato Adenovirus Infection, Mahmoud Soliman Salem Alghamri

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Human Adenoviruses (AdVs) are etiologic agents for respiratory tract, digestive tract, heart, and eye infections. Although most AdV infections are self-resolving, some infections progress to acute respiratory disease with up to 50% mortality, particularly in immunosuppressed people. Except for vaccines for serotypes, 4 and 7, serotypes that are prevalent in the military, no vaccines or therapeutics that specifically prevent or treat AdV infection exist. On the other hand, AdV remains the most common vector system used in gene therapy clinical trials worldwide and several AdV vectors show promise in phase III clinical trials. The majority of AdVs use the coxsackievirus …


Aircraft Thermal Management Using Liquefied Natural Gas, Sean Robert Nuzum Jan 2016

Aircraft Thermal Management Using Liquefied Natural Gas, Sean Robert Nuzum

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Many technological advances are expected to increase the capabilities of the future aircraft, both civilian and military. These improvements come in many forms such as new wing or fuselage shapes to improve lift or decrease drag. Other improvements are internal. One of these areas is the inclusion of advanced electronic systems for various roles. These changes affect a wide range of aircraft systems including, but not limited to avionics, power generation and thermal management. While these modifications promise to increase aircraft capabilities such as its range, payload or other key performance parameters, there are some significant drawbacks. One drawback is …


Analyzing Cognitive Workload Through Eye-Related Measurements: A Meta-Analysis, Melissa Patricia Coral Jan 2016

Analyzing Cognitive Workload Through Eye-Related Measurements: A Meta-Analysis, Melissa Patricia Coral

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Understanding cognitive workload has become a vital topic for researchers in developing future systems. Existing research has investigated the use of physiological measurements of the eye with cognitive workload, though a quantitative synthesis has yet to be performed. A meta-analysis was conducted to examine the effects of cognitive workload on eye-related measurements. The objective of this meta-analysis is not to determine a difference between the levels of workload, but to identify reliable measurements. Measurements through blinks, saccades, pupils, and fixations were examined. Twenty-two studies, contributing to a total of sixty entries, met the appropriate inclusion criteria for the meta-analysis. Findings …


Quantifying Amorphous Content Of Commercially Available Silicon Carbide Fibers, Ian Mark Wolford Jan 2016

Quantifying Amorphous Content Of Commercially Available Silicon Carbide Fibers, Ian Mark Wolford

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SiC/SiC ceramic matrix composites (CMCs) with potential applications at =2700°F (1482°C) are of significant interest to the Air Force. The high temperature performance of SiC fibers used within these composites is greatly affected by the presence of amorphous SiOC and free carbon in the fibers. Therefore quantification of this non SiC material in commercially available SiC fibers is extremely important. In this work Hi Nicalon, Hi-Nicalon Type-S, Tyranno-SA3, Cef-NITE, and Sylramic SiC fibers were studied. Changes in mass, grain size, and amorphous content were measured as a function of processing temperature and time. The amorphous material in each fiber was …


Aligned Carbon Nanotube Carpets On Carbon Substrates For High Power Electronic Applications, Betty Tun-Huan Quinton Jan 2016

Aligned Carbon Nanotube Carpets On Carbon Substrates For High Power Electronic Applications, Betty Tun-Huan Quinton

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Abstract Quinton, Betty Tun-Huan. Ph.D., Engineering Ph.D. Program, Wright State University, 2016. Aligned Carbon Nanotube Carpets On Carbon Substrates for High Power Electronic Applications. One of the driving forces behind nanotechnology research is the miniaturization of electronic devices. Electrical and thermal transport properties of device materials at micrometer and nanometer scales become very important in such applications. Carbon materials, especially carbon nanotubes (CNTs), have exceptionally low density and superior electrical, thermal, and mechanical properties. Vertically aligned CNTs attached to lightweight carbon substrates may hold the key to fully use these outstanding properties. However, the majority of studies reported to date …


Novel Cell Killing Mechanism Of Hydroxyurea In The Fission Yeast Schizosaccharomyces Pombe And Its Implications In Improving Antifungal Therapy, Amanpreet Singh Jan 2016

Novel Cell Killing Mechanism Of Hydroxyurea In The Fission Yeast Schizosaccharomyces Pombe And Its Implications In Improving Antifungal Therapy, Amanpreet Singh

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Hydroxyurea (HU, also known as hydroxycarbamide) is a well known ribonucleotide reductase (RNR) inhibitor that depletes cellular deoxyribonucleoside triphosphates (dNTPs, the building blocks of DNA). Depleted dNTP pools inside the proliferating cells stalls ongoing DNA replication forks, leading to the activation of the well-conserved DNA replication checkpoint (also known as intra-S phase checkpoint) pathway. One of the major functions of the checkpoint pathway is to protect ongoing forks from collapsing. Stalled forks, if not protected by the checkpoint pathway, lead to DNA damage and ultimately cell death. Thus it is believed that DNA damage resulting from collapsed forks is the …


Computer Graphics And Visualization Based Analysis And Record System For Hand Surgery And Therapy Practice, Venkatamanikanta Subrahmanyakartheek Gokavarapu Jan 2016

Computer Graphics And Visualization Based Analysis And Record System For Hand Surgery And Therapy Practice, Venkatamanikanta Subrahmanyakartheek Gokavarapu

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In this thesis, we have designed and developed a computer graphics and visualization based analysis and record system for hand surgery and therapy practice. In particular, we have designed and developed three novel technologies: (i) model-based data compression for hand motion records (ii) model-based surface area estimation of a human hand and (iii) an emulated study of hand wound area estimation. First, we have presented a new data compression technique to better address the needs of electronic health record systems, such as file storage and privacy. In our proposed approach, we will extract the patient's hand motion information and store …


An Approach To Implement Kahn's Technique With Dynamic Power Supply, Sowjanya Kommu Jan 2016

An Approach To Implement Kahn's Technique With Dynamic Power Supply, Sowjanya Kommu

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Radio-frequency power amplifiers are an integral part of today's communication systems. Primary importance is given to improve its efficiency and linearity, which are required for the effective signal transmission. Three main architectures on which, the efficiency of communication systems are based on are: (a) Kahn's technique, (b) Doherty's power amplifiers, and (c) Cheireix out-phasing modulation. Several schemes to implement these techniques exist in literature and their study is very diverse. In this thesis, a detailed literature survey on these techniques is presented, which includes their operation, properties, advantages, disadvantages, and areas of potential applications. This main objective of this thesis …


Interaction Of Due-B And Treslin During The Initiation Of Dna Replication, Sumeet Poudel Jan 2016

Interaction Of Due-B And Treslin During The Initiation Of Dna Replication, Sumeet Poudel

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The initiation of DNA replication is a highly regulated and coordinated process. To ensure that the entire genome is replicated only once per cell cycle, many replication proteins are assembled on the chromatin in a step-wise and cell cycle dependent manner. This process is controlled by interaction of replication proteins, post-translational modifications of the replication factors, control of cellular localization of the proteins, or replication factor degradation after their function terminates. Two kinases, CDK (cyclin dependent kinase) and DDK (Dbf4/Drf1 dependent kinase), play important roles during the initiation stage of DNA replication. The c-myc DNA unwinding element-binding protein (DUE-B) is …


Wikimatcher: Leveraging Wikipedia For Ontology Alignment, Helena Brooke Mccurdy Jan 2016

Wikimatcher: Leveraging Wikipedia For Ontology Alignment, Helena Brooke Mccurdy

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As the Semantic Web grows, so does the number of ontologies used to structure the data within it. Aligning these ontologies is critical to fully realizing the potential of the web. Previous work in ontology alignment has shown that even alignment systems utilizing basic string similarity metrics can produce useful matches. Researchers speculate that including semantic as well as syntactic information inherent in entity labels can further improve alignment results. This paper examines that hypothesis by exploring the utility of using Wikipedia as a source of semantic information. Various elements of Wikipedia are considered, including article content, page terms, and …


Personalized And Adaptive Semantic Information Filtering For Social Media, Pavan Kapanipathi Jan 2016

Personalized And Adaptive Semantic Information Filtering For Social Media, Pavan Kapanipathi

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Social media has experienced immense growth in recent times. These platforms are becoming increasingly common for information seeking and consumption, and as part of its growing popularity, information overload pose a significant challenge to users. For instance, Twitter alone generates around 500 million tweets per day and it is impractical for users to have to parse through such an enormous stream to find information that are interesting to them. This situation necessitates efficient personalized filtering mechanisms for users to consume relevant, interesting information from social media. Building a personalized filtering system involves understanding users' interests and utilizing these interests to …


Refining A Post-Stroke Pharmacological And Physical Treatment To Reduce Infarct Volume Or Improve Functional Recovery, Using Gene Expression Changes In The Peri-Infarct Region To Examine Potential Mechanisms In Male And Female Rats, Moner A. Ragas Jan 2016

Refining A Post-Stroke Pharmacological And Physical Treatment To Reduce Infarct Volume Or Improve Functional Recovery, Using Gene Expression Changes In The Peri-Infarct Region To Examine Potential Mechanisms In Male And Female Rats, Moner A. Ragas

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Stroke, a life-threatening medical condition, is the fifth-leading cause of death in the United States with an estimated annual cost of treatments above $70 billion. A combination of innovative approaches was used in our lab to optimize the pre-clinical stroke research design by choosing the most appropriate animal model and methodologies to increase the translational capability of the stroke research. The first study, modeled after ongoing clinical trials using fluoxetine, refined the appropriate timing of fluoxetine and ascorbic acid delivery if a rat was on simvastatin for 7 days pre-stroke and throughout the remainder of the study. Administration of fluoxetine …


Probabilistic Svm For Open Set Automatic Target Recognition On High Range Resolution Radar Data, Jason Daniel Roos Jan 2016

Probabilistic Svm For Open Set Automatic Target Recognition On High Range Resolution Radar Data, Jason Daniel Roos

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The application of Automatic Target Recognition (ATR) on High Range Resolution (HRR) radar data in a scenario that contains unknown targets is of great interest for military and civilian applications. HRR radar data provides greater resolution of a target as well as the ability to perform ATR on a moving target, which gives it an advantage over other imaging systems. With the added resolution of HRR comes the disadvantage that a change in the aspect angle or orientation results in greater changes in the collected data, making classical ATR more difficult. Closed set ATR on HRR radar data is defined …


Detecting Php-Based Cross-Site Scripting Vulnerabilities Using Static Program Analysis, Steven M. Kelbley Jan 2016

Detecting Php-Based Cross-Site Scripting Vulnerabilities Using Static Program Analysis, Steven M. Kelbley

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With the widespread adoption of dynamic web applications in recent years, a number of threats to the security of these applications have emerged as significant challenges for application developers. The security of developed applications has become a higher priority for both developers and their employers as cyber attacks become increasingly more prevalent and damaging. Some of the most used web application frameworks are written in PHP and have become major targets due to the large number of servers running these applications worldwide. A number of tools exist to evaluate PHP code for issues, however most of these applications are not …


From 2d To 3d: On The Development Of Flexible And Conformal Li-Ion Batteries Via Additive Manufacturing, Aaron Joseph Blake Jan 2016

From 2d To 3d: On The Development Of Flexible And Conformal Li-Ion Batteries Via Additive Manufacturing, Aaron Joseph Blake

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The future of electronic devices, such as smart skins, embedded electronics, and wearable applications, requires a disruptive innovation to the design of conventional batteries. This research was thus aimed at leveraging additive manufacturing as a means to invigorate the design of next-generation Li-ion batteries to meet the emerging requirements of flexible electronics. First, a state-of-the art approach for achieving flexible Li-ion batteries, using a robust, multi-walled carbon nanotube mat as current collector was demonstrated. A unique mechanical device was constructed to experimentally observe the correlation between mechanical fatigue and electrochemical stability. Points of failure in the conventional architecture were evaluated …


Measures Of User Interactions, Conversations, And Attacks In A Crowdsourced Platform Offering Emotional Support., Samir Yelne Jan 2016

Measures Of User Interactions, Conversations, And Attacks In A Crowdsourced Platform Offering Emotional Support., Samir Yelne

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Online social systems have emerged as a popular medium for people in society to communicate with each other. Among the most important reasons why people communicate is to share emotional problems, but most online social systems are uncomfortable or unsafe spaces for this purpose. This has led to the rise of online emotional support systems, where users needing to speak to someone can anonymously connect to a crowd of trained listeners for a one-on-one conversation. To better understand who, how and when users utilize these systems, and to evaluate their safety, this thesis offers a comprehensive examination of the characteristics …


Evidence That Myo-Inositol Plus Ethanolamine Elevates Plasmalogen Levels And Lends Protection Against Oxidative Stress In Neuro-2a Cells, Isaie Sibomana Jan 2016

Evidence That Myo-Inositol Plus Ethanolamine Elevates Plasmalogen Levels And Lends Protection Against Oxidative Stress In Neuro-2a Cells, Isaie Sibomana

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Plasmalogens are glycerophospholipids abundant in brain and heart tissues. Evidence suggests that they have antioxidant properties. Studies from our laboratory showed that rats treated with myo-inositol plus ethanolamine (ME) have elevated ethanolamine plasmalogens (PE-Pls) in brain and are protected against phosphine-induced oxidative stress. We hypothesized that ME elevates PE-Pls levels and protects against oxidative stress through oxidation of its vinyl ether bond. We tested this hypothesis in Neuro-2A cell culture and assessed the effects of treatments with myo-inositol (M), ethanolamine (Etn), or a combination (ME) on the: (1) effects on phospholipid (PL) classes, especially Etn PLs; (2) effects on cell …


Motion Planning And Control Of Differential Drive Robot, Kaamesh Kothandaraman Jan 2016

Motion Planning And Control Of Differential Drive Robot, Kaamesh Kothandaraman

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Motion planning and control of a differential drive robot in a supervised environment is presented in this thesis. Differential drive robot is a mobile robot with two driving wheels in which the overall velocity is split between left and right wheels. Kinematic equations are derived and implemented in Simulink to observe the theoretical working principle of the robot. A proportional controller is designed to control the motion of the robot, which is later implemented on a physical robot. Combination of linear velocity and orientation generates individual wheel velocities which are sent to the robot by wireless communication for its motion. …


Co-Transplantation Of Endothelial Progenitor Cells And Neural Progenitor Cells For Treating Ischemic Stroke In A Mouse Model, Jinju Wang Jan 2016

Co-Transplantation Of Endothelial Progenitor Cells And Neural Progenitor Cells For Treating Ischemic Stroke In A Mouse Model, Jinju Wang

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Ischemic stroke (IS) is a major cause of death and disability with limited and less effective therapeutics. Transplantation of stem cells, such as neuronal progenitor cells (NPCs) and endothelial progenitor cells (EPCs), is promising for treating IS. It is well known that neurogenesis and angiogenesis are critical for cerebral repair following ischemic injury. However, whether co-transplantation of EPCs and NPCs has synergistic effects remains unclarified. In addition, the PI3K/Akt pathway participates in modulating a widely range of cellular functions such as anti-apoptotic and anti-oxidant. The signal pathways responsible for the effects of grafted NPCs and EPCs are also waiting for …


An Adapted Approach To Process Mapping Across Alloy Systems And Additive Manufacturing Processes, Luke Charles Sheridan Jan 2016

An Adapted Approach To Process Mapping Across Alloy Systems And Additive Manufacturing Processes, Luke Charles Sheridan

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The continually growing market for metal components fabricated using additive manufacturing (AM) processes has called for a greater understanding of the effects of process variables on the melt pool geometry and microstructure in manufactured components for various alloy systems. Process Mapping is a general approach that traces the influence of process parameters to thermal behavior and feature development during AM processing. Previous work has focused mainly on Ti-6Al-4V (Ti64), but this work uses novel mathematical derivations and adapted process mapping methodologies to construct new geometric, thermal, and microstructural process maps for Ti64 and two nickel superalloy material systems. This work …


Mining And Analyzing Subjective Experiences In User Generated Content, Lu Chen Jan 2016

Mining And Analyzing Subjective Experiences In User Generated Content, Lu Chen

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Web 2.0 and social media enable people to create, share and discover information instantly anywhere, anytime. A great amount of this information is subjective information -- the information about people's subjective experiences, ranging from feelings of what is happening in our daily lives to opinions on a wide variety of topics. Subjective information is useful to individuals, businesses, and government agencies to support decision making in areas such as product purchase, marketing strategy, and policy making. However, much useful subjective information is buried in ever-growing user generated data on social media platforms, it is still difficult to extract high quality …


Modular Multi-Signal Tracking Pulse Descriptor Word (Pdw) Generator With Field Programmable Gate Array (Fpga) Implementation, Justin Darrell Pelan Jan 2016

Modular Multi-Signal Tracking Pulse Descriptor Word (Pdw) Generator With Field Programmable Gate Array (Fpga) Implementation, Justin Darrell Pelan

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As signal spectra become dense, the task of tracking and identifying radars becomes increasingly cumbersome. The variety of radars in modern theaters of war compound the task due to simultaneous operation. Real-time processing of large data sets prove difficult for sequential systems, and the parallelism of Field Programmable Gate Arrays (FPGAs) becomes an attractive option. To mitigate the increasing complexity of this task, this design proposes an FPGA architecture to produce pulse descriptor words (PDW) for up to eight independent radio frequency signals that can be used in near-real-time processing. Focusing on digital hardware techniques and modular design allow for …