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Soft Matter Films Interfaced To Electronic Devices: Capacitance-Modulated Field Effect Transistors Integrating Protein Layers, Gerardo Palazzo, Luisa Torsi, Maria Magliulo, Antonia Mallardi

Colloidal, Macromolecular & Biological Gels: Formulation, Properties & Applications

Soft matter systems interfaced to an electronic device are presently one of the most challenging research activity that has relevance not only for fundamental studies but also for the development of highly performing bio-sensors.

Layers of proteins anchored on solid surfaces have small capacitance that undergoes to only minute changes as the ligand–protein complex is formed.

For properly designed systems, the protein layer represents smallest capacitance in a series of capacitors and as such dominates the overall capacitance. When such a protein layer is integrated in a Field Effect Transistor (FET) transduction is remarkably sensitive as the transistor output current …