Engineering Commons^™

Ergonomic Analysis Of Mobile Cart–Assisted Stocking Activities Using Electromyography, Sohyung Cho

SIUE Faculty Research, Scholarship, and Creative Activity

Workers in grocery stores are exposed to numerous musculoskeletal risks that can be reduced using assistive devices while performing stocking tasks. A regional grocery store has recently deployed a mobile cart without comprehension of its ergonomic impact on workers, which this article investigates using normalized electromyography data (%MVC). This article studies not only ergonomic impact based on %MVC values but also work performance represented by a muscle force metric (MFM). The results from this study showed highest muscle groups in %MVC and MFM were the erector spinae and triceps. Interestingly, muscle activations on erector spinae were reduced when mobile cart …

On Valuing Biopharmaceutical Product Pipelines: An Effectuation Model And Evidence, Mark J. Ahn, Anne S. York, Wei Wu, Yulianto Suharto, Tugrul Unsal Daim

Engineering and Technology Management Faculty Publications and Presentations

New creative approaches are needed to manage emerging biotechnology innovations, regulations, and payor environments to enhance product pipeline productivity, valuation, and risk management. Biopharmaceutical firms must make dynamic resource allocation decisions on their relative levels of internal R&D and external strategic alliances in furthering their pipelines. As the predominant method of using discounted cash flow (DCF) methodologies may lead to chronic underinvestment and performance, we evaluated the integration of traditional DCF with an effectuation model of analysis. Unlike traditional financial models that begin with the end goal of assumed known cash flows and recursively solve for portfolio optimization, the effectuation …

The Prediction Predicament, William "Ike" Eisenhauer

Engineering and Technology Management Faculty Publications and Presentations

The article focuses on the prediction of predicament in terms of forecasting at industrial engineering level. Topics discussed include business optimize resources via forecasting; audience who cannot comprehend the methodology used for forecasting in healthcare operations; and use of forecasting for performance measurement.

Analysis Of A Clinically Failed, Mechanically Intact, Reconstructive Compression Plate, Bharadwaj Cheruvu, Sunil Karmacharya, Richard T. Laughlin, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

A reconstructive orthopedic bone plate was submitted for analysis. Traditional failure analysis methods were used to assess the mode of the plate failure. Metallographic investigation of the plate was carried out in this report. Since limited data was available in the literature and clinical data related to subject demography, date of removal as well as reasons for removal unknown, in depth analysis was not possible. However, the plate was received in in-tact condition with minor biological deposits and scratches, it is speculated that the failure of the plate may have been due to biological/clinical reasons, likely infection, rejecting the device …

Haptics-Based Cataract Surgery Simulator, Jia Luo

Link Foundation Modeling, Simulation and Training Fellowship Reports

Surgical training using computer-based simulators are being adopted by many medical specialties, mainly because they offer several advantages to traditional training methods involving animals or cadavers. This article focuses on the design and implementation of a haptics-based cataract surgery simulator.

The Time Has Come For Nursing Engineering, William "Ike" Eisenhauer

Engineering and Technology Management Faculty Publications and Presentations

The article discusses the need for healthcare and educational organizations to create nursing engineering program. Topics discussed include successes in healthcare systems as engineers and healthcare professionals, integration of industrial engineering or lean and Six Sigma courses into nursing programs of the University of Alabama and modern healthcare system and modern healthcare participants that can be addressed by the new profession.

Velaglucerase Alfa (Vpriv) Enzyme Replacement Therapy In Patients With Gaucher Disease: Long-Term Data From Phase Iii Clinical Trials, Derralynn A. Hughes, Derlis Gonzalez, Elena A. Lukina, Atul Mehta, Madhulika Kabra, Deborah Elstein, Isaac Kisinovsky, Pilar Giraldo, Ashish Bavdekar, Thomas N. Hangartner, Nan Wang, Eric Crombez, Ari Zimran

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Type 1 Gaucher disease is an inherited lysosomal enzyme deficiency with variable age of symptom onset. Common presenting signs include thrombocytopenia, anemia, hepatosplenomegaly, bone abnormalities, and, additionally in children, growth failure. Fifty-seven patients aged 3–62 years at the baseline of two phase III trials for velaglucerase alfa treatment were enrolled in the single extension study. In the extension, they received every-other-week velaglucerase alfa intravenous infusions for 1.2–4.8 years at 60 U/kg, although 10 patients experienced dose reduction. No patient experienced a drug-related serious adverse event or withdrew due to an adverse event. One patient died following a convulsion that was …

Safety And Efficacy Results Of Switch From Imiglucerase To Velaglucerase Alfa Treatment In Patients With Type 1 Gaucher Disease, Deborah Elstein, Atul Mehta, Derralynn A. Hughes, Pilar Giraldo, Joel Charrow, Laurie Smith, Suma P. Shankar, Thomas N. Hangartner, Yune Kunes, Nan Wang, Eric Crombez, Ari Zimran

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Gaucher disease (GD) is a lysosomal storage disorder; symptomatic patients with type 1 GD need long-term disease-specific therapy of which the standard of care has been enzyme replacement therapy (ERT). Thirty-eight of 40 patients (aged 9–71 years) clinically stable on ERT with imiglucerase, safely switched to a comparable dose of velaglucerase alfa (units/kg) during TKT034, a 12-month, open-label clinical study, and for 10–50 months in an extension study. The most common adverse events (AEs) judged to be drug-related in the extension were fatigue and bone pain. No drug-related serious AEs were reported. No AEs led to study withdrawal. At 24 …

Active Learning In Supply Chain Management Course, Farnaz Ghazi-Nezami, Mehmet Bayram Yildirim

Industrial & Manufacturing Engineering Presentations And Conference Materials

Active Learning in the Supply Chain Management Course. This paper presents a new active learning approach implemented in the Supply ChainManagement (SCM) course in the Industrial and Manufacturing Engineering Department.Previously, in this course the fundamentals of supply chain and logistics, drivers of supply chainperformance and analytical tools necessary to develop solutions for a variety of SCM and designproblems were mainly covered through class lectures and case study discussions. In the past fewyears, due to the growth in the needs of the organizations to “Lean” principles, the course wasmodified to satisfy this requirement more efficiently. For this purpose a new hands …

Toe Joint Replacement Models, Tarun Goswami, Allison L. Van Horn, Alexander O. Sheets

Biomedical, Industrial & Human Factors Engineering Faculty Publications

In various embodiments, provided are implantable devices for replacing all or a portion of a metatarsophalangeal joint, comprising (i) a metatarsal component comprising a Substan tially convex bearing Surface; or (ii) a phalanx component comprising a Substantially concave bearing Surface; or (iii) both. In various embodiments, also provided are methods of treating hallux Valgus by replacing all or a portion of a meta tarsophalangeal joint with one or more of the provided implantable devices.

Developing Entrepreneurial Thinking In Engineering Students By Utilizing Integrated Online Modules, Ronald S. Harichandran, Maria-Isabel Carnasciali, Nadiye O. Erdil, Cheryl Q. Li, Jean Nocito-Gobel, Samuel Bogan Daniels

Mechanical and Industrial Engineering Faculty Publications

An approach to develop entrepreneurial thinking skills in engineering students by integrating online modules into existing courses is described. Eighteen online modules covering a variety of topics will be developed. Developers for the modules are selected by reviewing proposals submitted in response to a broadly distributed request for proposals. Developers undergo extensive training before embarking upon module development. Students will complete each standalone module outside of class hours. Instructors who deploy a module in their course will develop contextual course assignments that reinforce concepts covered in the modules. These instructors also undergo training and are assisted by an external consultant. …

Don't Go Chasing Big Waterfalls, William "Ike" Eisenhauer

Engineering and Technology Management Faculty Publications and Presentations

The article focuses on the importance of simpler health systems in the U.S. Topics discussed include success of simple systems as they are well-understood, improvement of simple systems by coupling them together, handling more patient cases by larger systems by the medical laboratory technicians giving complicated results and designing simple systems by health system engineers to deal with fewer problematic cases of patients with more efficacy.

Warpage And Shape Distortion In Laser Metal Sintering, Xuan Wang

Industrial and Manufacturing Engineering

Selective Laser Sintering (SLS) is the primary method to fabricate metal and ceramic components in additive manufacturing. Due to the anisotropy of powder material, the sintering rate difference will inevitably causes shape change, distortion , and other defects of sintered parts. In this paper, a continuum model was developed to simulate the SLS process. The developed model has been successful to predict sintering kinetics. The impact of processing parameters, such as laser power, scanning speed, hatching distance, and particle size has been studied . The proposed method provides an innovative tool to optimize SLS process parameters.

Design, Programming, And User-Experience, Kaila G. Manca

Honors Scholar Theses

This thesis is a culmination of my individualized major in Human-Computer Interaction. As such, it showcases my knowledge of design, computer engineering, user-experience research, and puts into practice my background in psychology, com- munications, and neuroscience.

I provided full-service design and development for a web application to be used by the Digital Media and Design Department and their students.This process involved several iterations of user-experience research, testing, concepting, branding and strategy, ideation, and design. It lead to two products.

The first product is full-scale development and optimization of the web appli- cation.The web application adheres to best practices. It was …

The Development Of A Workplace Resilience Instrument, Larry Mallak

Faculty Research and Creative Activities Award (FRACAA)

The Workplace Resilience Instrument (WRI) has the potential to provide organizations and managers a useful tool for improving workplace resilience and helping employees achieve their potential.

Oculomotor Neurocircuitry, A Structural Connectivity Study Of Infantile Nystagmus Syndrome, Nasser H. Kashou, Angelica R. Zampini

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Infantile Nystagmus Syndrome (INS) is one of the leading causes of significant vision loss in children and affects about 1 in 1000 to 6000 births. In the present study, we are the first to investigate the structural pathways of patients and controls using diffusion tensor imaging (DTI). Specifically, three female INS patients from the same family were scanned, two sisters and a mother. Six regions of interest (ROIs) were created manually to analyze the number of tracks. Additionally, three ROI masks were analyzed using TBSS (Tract-Based Spatial Statistics). The number of fiber tracks was reduced in INS subjects, compared to …

Syllabus: Introduction To Mechanical And Industrial Engineering, Erin Baker

Sustainability Education Resources

Student teams will explore engineering analysis and design under the theme of Engineering Sustainability: Energy and the Environment, incorporating economics, environmental impacts, and social concerns. ENGIN 113 is intended to introduce students to the fields of Mechanical Engineering and Industrial Engineering, and to provide students with important skills that they will need to be successful in college and the professional world. The specific course objectives are to:  Develop effective teamwork skills, including peer- and self-evaluation.  Practice critical thinking and engineering problem solving.  Take a systems approach to design, incorporating economics, environment, and social concerns  Develop information …

Classroom Exercise: Intro To Mechanical And Industrial Engineering, Erin Baker

Sustainability Education Resources

This classroom exercise was developed for Introduction to Mechanical and Industrial Engineering; Engineering Sustainability: Energy and the Environment. This is a freshman class with a class size of about 200. It is intended to get students to think critically about energy in the economy; to recognize the power of technological change; and to inspire them to work toward solving climate change.

A Probabilistic Fracture Assessment Of Vertebral Cortical Bone, Tarun Goswami, Isaac Mabe

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Cortical bone is a material with a porous structure. The presence of pores creates local stress concentrations and the likelihood of premature failure. Assuming that pores are present in all bone, vertebral endplates, for example, can subside. Subsidence has taken place at rates as high as 77 percent. A computational probabilistic assessment of the pore size distribution and their contribution to the fracture toughness has been presented in this paper. A Monte Carlo simulation was used to develop and assign random pores. Also the model compared crack sizes to the thickness of the cortical bone present as a limiting case. …

Traci Impact Assessment Of Transportation Manufacturing Nexus In The U.S.: A Supply Chain-Linked Cradle-To-Gate Lca, Yong Shin Park, Gokhan Egilmez

Mechanical and Industrial Engineering Faculty Publications

Sustainable transportation is an inevitable component of sustainable development intitiatives for mitigating the climate change impacts and stabilizing the rising carbon emissions thus global temperature. In this context, comprehensive analysis of the environmental impact of transportation can play a critical role towards quantifying the midpoint environmental and human health related impacts associated with the transportation activities triggered by manufacturing sectors. This study traces the life cycle impact of the U.S. transportation and manufacturing sectors’ nexus using Tool for the Reduction and Assessment of Chemicals and Other Environmental Impacts (TRACI) in the context of the Economic Input-Output Life Cycle Assessment (EIO-LCA) …

Bus Rapid Transit (Brt) Toolbox: Brt Person Throughput-Vehicle Congestion Tradeoffs, Li Jingquan, H.-S. Jacob Tsao, Ching-Yao Chan, Kun Zhou, Wei-Bin Zhang

Faculty Publications

This report documents a research effort to understand the current practice and issues associated with Bus Rapid Transit (BRT) planning and deployment. It reviewed the design options incorporated into existing BRT deployments across California and the nation. The project team interviewed practitioners of California Department of Transportation (Caltrans) Districts and transit agencies to understand the BRT project approval decision-making process, the impacts of BRT implementation and the Measures of Effectiveness (MOEs) for transit and non-transit system performance. The studies revealed that though Caltrans and transit agencies do use a similar set of MOEs for the evaluation of BRT projects, the …

A General Intuitive Design Pattern For Optimally Sequencing Treatment Combinations In 2k Factorial Experiment And A Simple Estimation Algorithm, H.-S. Jacob Tsao, Minnie Patel

Faculty Publications

The number of model parameters of a 2k factorial design grows exponentially. When the number of factors is large, numerous higher-order interactions constitute a vast majority of the model parameters while many of them do not exist or are insignificant. The classic methods of fractional factorial designs, Plackett–Burman designs, Taguchi designs, etc. seek an already developed and often cataloged design that fits exactly the problem being tackled or select a design that fits it the most. Most, if not all, of these designs were developed in absence of convenient computation tools and enjoy computational simplicity. The necessary number of treatment …

A Simulation-Based Approach To Risk Assessment And Mitigation In Supply Chain Networks, Mamadou Seck, Ghaith Rabadi, Christian Koestler

Engineering Management & Systems Engineering Faculty Publications

We present in this paper a simulation-based approach to evaluate the risk associated with supply chain disruptions caused by failures in some supply chains nodes and measure the impact of such disruptions on supply chain key performance measures (KPIs) of interest. The proposed framework enables analysts and managers to repeatedly assess the risk to their supply chains based on various simulated scenarios and identify the most critical nodes whose disruption will have the highest impact on the KPIs of interest. As a result, companies can focus on the most critical supply chain assets and develop targeted mitigation plans that minimize …

Challenges For Developing Complex System Governance, Charles B. Keating, Polinpaplinho F. Katina, Joseph M. Bradley, Sila Çetinkaya (Ed.), J. K. Ryan (Ed.)

Engineering Management & Systems Engineering Faculty Publications

This paper examines the challenges and practice implications for Complex System Governance (CSG). CSG is presented as an emerging field focused on the design, execution, and evolution of the higher order (metasystem) functions necessary to provide control, communication, coordination, and integration of a complex system. This paper is focused on three primary objectives. First, we introduce the complex system problem domain that the CSG field is being designed to address. The pervasiveness of this problem domain is demonstrated by a short examination of the water utilities sector. Second, we expound the nature of CSG and an emerging reference model …

Chemical Storage Of Wind Energy By Renewable Methanol Production: Feasibility Analysis Using A Multi-Criteria Decision Matrix, Michael J. Matzen, Mahdi H. Alhajji, Yaşar Demirel

Department of Chemical and Biomolecular Engineering: Faculty Publications

This study is for the technoeconomic analysis of an integral facility consisting of wind energy-based electrolytic hydrogen production, bioethanol-based carbon dioxide capture and compression, and direct methanol synthesis. ASPEN Plus was used to simulate the facility producing 97.01 mt (metric tons) methanol/day using 138.37 mt CO₂/day and 18.56 mt H₂/day. A discounted cash flow diagram for the integral facility is used for the economic analysis at various hydrogen production costs and methanol selling prices. The feasibility analysis is based on a multi-criteria decision matrix consisting of economic and sustainability indicators comparing renewable and non-renewable methanol productions. …

Multi-Period Cell Loading And Job Sequencing In A Cellular Manufacturing System, Gokhan Egilmez, Gürsel A. Süer

Mechanical and Industrial Engineering Faculty Publications

In this paper, a multi-period cell loading problem is addressed, where the objectives are to minimise the number of tardy jobs (n_T) in a multi-period planning horizon and optimise the scheduling of tardy jobs. Three cell loading and job scheduling strategies are proposed and tested with two newly developed mixed integer programming models. Additionally, three types of due dates (tight, medium and loose) and three different demand levels were considered. Finally, two tardy job assignment methods were proposed to observe the impact on n_T. Case problems were solved based on minimising n_T, T_{max …}

Reducing Uncertainty In Technology Selection For Long Life Cycle Engineering Designs, Halil I. Ozdemir, C. Ariel Pinto, Resit Unal, Charles B. Keating, Colin Britcher, Sila Çetinkaya (Ed.), J. K. Ryan (Ed.)

Engineering Management & Systems Engineering Faculty Publications

The best capabilities are usually achieved by having the latest technologies in defense systems. However, including the new, usually immature, technologies in a system design does not always easily result in achieving the capabilities at the right level, at an affordable cost, and in a timely manner. Many programs have suffered from immature technologies as cost overruns, late or no deliveries, and poor performance levels. Another impact of technology selection appears as obsolescence after the deployment of systems, or even before the deployment of the system. As the technologies of a system become obsolete, the cost of maintaining the system …

A Comparison Of Combined Overlap Block Fuzzy Cognitive Maps (Cobfcm) And Combined Overlap Block Neutrosophic Cognitive Map (Cobncm) In Finding The Hidden Patterns And Indeterminacies In Psychological Causal Models: Case Study Of Adhd, Hojjatollah Farahani, Florentin Smarandache, Lihshing Leigh Wang

Branch Mathematics and Statistics Faculty and Staff Publications

In spite of researchers’ concerns to find causalities, reviewing the literature of psychological studies one may argue that the classical statistical methods applied in order to find causalities are unable to find uncertainty and indeterminacies of the relationships between concepts.

In this paper, we introduce two methods to find effective solutions by identifying “hidden” patterns in the patients’ cognitive maps. Combined Overlap Block Fuzzy Cognitive Map (COBFCM) and Combined Overlap Block Neutrosophic Map (COBNCM) are effective when the number of concepts can be grouped and are large in numbers. In the first section, we introduce COBFCM, COBNCM, their applications, and …

Size Effects In Human Visual Inspection For Micro/Meso Scale Parts, Sri Harsha Kavuri

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Visual inspection has been a major method of quality control in conventional manufacturing processes for the last fifty years. Utilizing trained human inspectors to perform this visual inspection has been the most effective means of maintaining quality control. Extensive research has been performed to understand the factors that influence the human inspection process.

In the recent years, there has been a significant emphasis on manufacturing at the smaller end of the size-spectrum such as Micro and Meso scale manufacturing. Quality control at becomes a challenging task due to the extremely small sizes. Several automated visual inspection techniques have been proposed …