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2011

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Full-Text Articles in Engineering

Microbeam Radiation Therapy: A Monte Carlo Study Of The Influence Of The Source, Multislit Collimator, And Beam Divergence On Microbeams, Heidi Nettelbeck, George Takacs, Michael Lerch, Anatoly Rosenfeld Nov 2011

Microbeam Radiation Therapy: A Monte Carlo Study Of The Influence Of The Source, Multislit Collimator, And Beam Divergence On Microbeams, Heidi Nettelbeck, George Takacs, Michael Lerch, Anatoly Rosenfeld

George Takacs

Microbeam radiation therapy (MRT) is a new oncology method currently under development for the treatment of inoperable pediatric brain tumors. Monte Carlo simulation, or the computational study of radiation transport in matter, is often used in radiotherapy to theoretically estimate the dose required for treatment. However, its potential use in MRT dose planning systems is currently hindered by the significant discrepancies that have been observed between measured and theoretical dose and the PVDR (peak to valley dose ratio). The need to resolve these discrepancies is driven by the desirability of making MRT available to humans in the next few years. …


Effect Of Transverse Magnetic Fields On Dose Distribution And Rbe Of Photon Beams: Comparing Penelope And Egs4 Monte Carlo Codes, Heidi Nettelbeck, George Takacs, Anatoly Rosenfeld Nov 2011

Effect Of Transverse Magnetic Fields On Dose Distribution And Rbe Of Photon Beams: Comparing Penelope And Egs4 Monte Carlo Codes, Heidi Nettelbeck, George Takacs, Anatoly Rosenfeld

George Takacs

The application of a strong transverse magnetic field to a volume undergoing irradiation by a photon beam can produce localized regions of dose enhancement and dose reduction. This study uses the PENELOPE Monte Carlo code to investigate the effect of a slice of uniform transverse magnetic field on a photon beam using different magnetic field strengths and photon beam energies. The maximum and minimum dose yields obtained in the regions of dose enhancement and dose reduction are compared to those obtained with the EGS4 Monte Carlo code in a study by Li et al (2001), who investigated the effect of …