Engineering Commons^™

Optimizing Sequential Dual Tracer P.E.T. Studies Using A Combined 2d/3d Imaging Protocol, John W. Wilson, S. Borges-Neto, Timothy G. Turkington, James G. Colsher, R. E. Reiman, R. E. Coleman

Mining Engineering Faculty Research & Creative Works

We have investigated a combined 2D/3D protocol for minimizing contamination in dual tracer P.E.T. studies in which the tracers are administered on a timescale that is short compared to the half-lives. We have performed a series of phantom studies on an Advance and a Discovery ST (GE Healthcare Technologies), using a torso phantom with cardiac insert (Data Spectrum Corporation) to simulate a combined FDG and NH3 scan protocol for a patient with ischemia. The phantom was imaged in a series of alternating 2D/3D acquisitions as it decayed over 6 half-lives. By comparing 2D and 3D images, we have verified that …