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Application Of Bootstrap Resampling In Fmri, Arthika Bappal
Application Of Bootstrap Resampling In Fmri, Arthika Bappal
Theses
This thesis demonstrates the use of the bootstrap resampling technique considering temporal dependency in the fMRI data to determine the reliability and confidence interval of fMRI parameters. Traditionally, the test-retest method has been used to reliably detect active voxels in the fMRI image of the brain, which is based on repetitive experimentation. The main concern with the test-retest method is the reproducibility of data over these multiple repetitions. Fatigue, habituation, motion artifacts, and repositioning errors are few of the factors, which can affect the reproducibility of data.
The conventional bootstrap resampling technique is based on the assumption that the dataset …
Development Of Fmri Compatible Lower Body Negative Pressure System, Pratap Singh Kunwar
Development Of Fmri Compatible Lower Body Negative Pressure System, Pratap Singh Kunwar
Theses
The lower body negative pressure (LBNP) system provides a controlled, measured orthostatic stress to the cardiovascular system, which can be used with a magnetic resonance imaging (MRI) machine to study cardiovascular and cerebrovascular responses to graded LBNP. In the past, even though functional MRI (fMRI) was considered as one of the best modalities with which to measure small metabolic changes in the brain, it has not been used with an LBNP system to measure cerebrovascular changes. This was due to the lack of an fMRI compatible LBNP system.
In this project, an tMRI compatible LBNP system was first constructed without …