Open Access. Powered by Scholars. Published by Universities.®
- Institution
- Keyword
-
- Abdomen (2)
- Animals (2)
- Diabetes Mellitus (2)
- Inbred BALB C (2)
- Interleukin-10 (2)
-
- Islets of Langerhans (2)
- Mice (2)
- Type 1 (2)
- Wheat gluten (2)
- High shear reactor. (1)
- 2 (1)
- 2' bipyridine derivative (1)
- Accelerates (1)
- Adenosine triphosphate (1)
- Adjunct (1)
- Animal studies (1)
- Backscattering (1)
- Base Sequence (1)
- Blood flow (1)
- CPR (1)
- Cobalt-alloy (1)
- Computer modeling (1)
- Computer simulation models (1)
- Corn zein (1)
- Corn-zein (1)
- Counterpulsation (1)
- Crested wheatgrass (1)
- Crosses (1)
- DNA (1)
- Degradation (1)
Articles 1 - 18 of 18
Full-Text Articles in Engineering
In Vitro Activities Of 2,2'-Bipyridyl Analogs Against Mycobacterium Leprae, Arvind Madhav Dhople, Maria Antonia Ibáñez, Anita A. Dhople
In Vitro Activities Of 2,2'-Bipyridyl Analogs Against Mycobacterium Leprae, Arvind Madhav Dhople, Maria Antonia Ibáñez, Anita A. Dhople
Biomedical Engineering and Sciences Faculty Publications
In vitro susceptibility of Mycobacterium leprae to two bipyridyl analogs was studied by using two biochemical parameters to measure the metabolic activity of the organism. VUF-8514 at 0.16 μg/ml, but not VUF-8842, completely inhibited the metabolic activity of M. leprae, and the action was bactericidal. When compared to rifampin (MIC 0.3 μg/ml), VUF-8514 was equally bactericidal against M. leprae.
A Prototype Computational Phantom To Create Digital Images For Research And Training In Diagnostic Radiology, Charles F. Babbs
A Prototype Computational Phantom To Create Digital Images For Research And Training In Diagnostic Radiology, Charles F. Babbs
Weldon School of Biomedical Engineering Faculty Working Papers
Research in the processing, compression, transmission, and interpretation of digital radiographic images require the testing and evaluation of a wide variety of images, varying both in format and in spatial resolution. If receiver operating characteristic (ROC) analysis or a related method is used to evaluate the performance of observers using novel vs. conventional displays, large numbers of test images containing known abnormalities are required. This report describes a convenient, inexpensive, and reproducible source of test images, having any desired resolution and containing precisely defined abnormalities of unlimited subtlety. The images are generated by computing x-ray transmission through mathematically defined, three …
High Shear Mixing Reactor For Glycerolysis, Hossein Noureddini
High Shear Mixing Reactor For Glycerolysis, Hossein Noureddini
Papers in Biomaterials
lnrcreasEd ervironmental awareness and depletion of resources are driving industry to develop aiternative fuels from renew ble resources that are environmentally more acceprable. Esters of fatty acids (biodiesel)-derived from the traiisesterification of vegetable oils, have properties 3imi:ar to cornponents of petrolium based dieselfuel. Cost has been a Cost has been major factor inslowing down the commercialization of biodiesel. In order to improve the eiuIlulliy ui Illis process two iactors wcrc invcarigated in this study: 1) use of beef tallow as raw mzlerial and 2) by-product utilization. Glycerol is the by-product of the esterlficatiun Drocesg In this work the feasibility of …
Maximum Surface Storage Provided By Crop Residue, John E. Gilley, Eugene R. Kottwitz
Maximum Surface Storage Provided By Crop Residue, John E. Gilley, Eugene R. Kottwitz
Biological Systems Engineering: Papers and Publications
Small ponds created by crop residue serve to store water on upland areas. The present study is conducted to identify the maximum surface storage provided by crop residue. Equations for estimating surface storage are derived assuming that residue elements were oriented end to end, at uniform intervals, in a direction perpendicular to flow. Separate equations are developed for conditions where average slope was greater than or equal to residue cover, or less than residue cover. Both equations relate average surface-storage depth to residue cover, residue diameter, and average slope. Data to test the reliability of the equations are obtained in …
Hydraulic Conditions Required To Move Unanchored Residue Materials, John E. Gilley, E. R. Kottwitz, G. A. Wieman
Hydraulic Conditions Required To Move Unanchored Residue Materials, John E. Gilley, E. R. Kottwitz, G. A. Wieman
Biological Systems Engineering: Papers and Publications
Hydraulic conditions required to initiate movement of unanchored residue materials are identified in the present study. Selected amounts of corn, cotton, pine needles, sorghum, soybean, sunflower, and wheat residue are placed in a flume on a sand surface, and flow is then introduced at the top of the flume in progressive increments. The discharge rate and flow velocity necessary to cause residue movement are determined. The ratio of critical flow depth to residue diameter, critical Reynolds number, critical shear stress, dimensionless shear stress, and boundary Reynolds number are calculated from hydraulic measurements. Regression equations are developed to relate dimensionless shear …
Non‐Rayleigh Statistics Of Ultrasonic Backscattered Echo From Tissues, V. Manjo Narayanan, Robert C. Molthen, P. M. Shankar, J. M. Reid
Non‐Rayleigh Statistics Of Ultrasonic Backscattered Echo From Tissues, V. Manjo Narayanan, Robert C. Molthen, P. M. Shankar, J. M. Reid
Biomedical Engineering Faculty Research and Publications
The envelope of the backscattered signal from tissues can exhibit non‐Rayleigh statistics if the number density of scatterers is small or if the variations in the scattering cross sections are random. The K distribution which has been used extensively in radar, is introduced to model this non‐Rayleigh behavior. The generalized K distribution is extremely useful since it encompasses a wide range of distributions such as Rayleigh, Lognormal, and Rician. Computer simulations were conducted using a simple one‐dimensional discrete scatteringmodel to investigate the properties of the echo envelope. In addition to cases of low number densities, significant departures from Rayleigh statistics …
Production Of Interleukin 10 By Islet Cells Accelerates Immune-Mediated Destruction Of Beta Cells In Nonobese Diabetic Mice., Lise Wogensen, Myung-Shik Lee, Nora Sarvetnick
Production Of Interleukin 10 By Islet Cells Accelerates Immune-Mediated Destruction Of Beta Cells In Nonobese Diabetic Mice., Lise Wogensen, Myung-Shik Lee, Nora Sarvetnick
Journal Articles: Regenerative Medicine
The T helper type 2 (Th2) cell product interleukin 10 (IL-10) inhibits the proliferation and function of Th1 lymphocytes and macrophages (M phi). The nonobese diabetic mouse strain (NOD/Shi) develops a M phi and T cell-dependent autoimmune diabetes that closely resembles human insulin-dependent diabetes mellitus (IDDM). The objective of the present study was to explore the consequences of localized production of IL-10 on diabetes development in NOD/Shi mice. Surprisingly, local production of IL-10 accelerated the onset and increased the prevalence of diabetes, since diabetes developed at 5-10 wk of age in 92% of IL-10 positive I-A beta g7/g7, I-E- mice …
Laser Assisted Pd Seeding For Electroless Plating On Siq2, A. G. Schrott, B. Braren, Ravi F. Saraf
Laser Assisted Pd Seeding For Electroless Plating On Siq2, A. G. Schrott, B. Braren, Ravi F. Saraf
Ravi Saraf Publications
Excimer laser pulses with wavelengths of 248 and 308 nm were used to selectively seed Pd on SiO2 surfaces, making them suitable for electroless plating. This novel seeding process for insulating materials is accomplished with the sample immersed in the seeding solution, and occurs only on the areas of the substrate that are illuminated (through the liquid) by the laser light. The Pd content of the seeded samples increased with the number of pulses, but was rather independent of repetition rate. The deposition rate showed a dependence with wavelength consistent with a defect driven mechanism for electron excitation through …
Pancreatic Islet Production Of Murine Interleukin-10 Does Not Inhibit Immune-Mediated Tissue Destruction., Myung-Shik Lee, Lise Wogensen, Judith Shizuru, Michael B.A. Oldstone, Nora Sarvetnick
Pancreatic Islet Production Of Murine Interleukin-10 Does Not Inhibit Immune-Mediated Tissue Destruction., Myung-Shik Lee, Lise Wogensen, Judith Shizuru, Michael B.A. Oldstone, Nora Sarvetnick
Journal Articles: Regenerative Medicine
IL-10 inhibits macrophage-dependent antigen presentation, cytokine production, and generation of allospecific cells in vitro. These findings have lead to the widespread expectation that IL-10 may be a useful immunosuppressive agent to inhibit allograft rejection or autoimmunity in vivo. We used two experimental paradigms to study effects of murine IL-10 on in vivo immune responses. First, fetal pancreata or adult pancreatic islets from transgenic mice expressing IL-10 in pancreatic beta cells (Ins-IL-10 mice) were grafted across the MHC barrier to examine if IL-10 could inhibit allograft rejection. Second, Ins-IL-10 mice were crossed with transgenic mice expressing lymphocytic choriomeningitis virus (LCMV) antigens …
Intergranular Corrosion-Fatigue Failure Of Cobalt-Alloy Femoral Stems. A Failure Analysis Of Two Implants, Jeremy L. Gilbert, Christine A. Buckley, Joshua J. Jacobs, Kim C. Bertin, Michael R. Zernich
Intergranular Corrosion-Fatigue Failure Of Cobalt-Alloy Femoral Stems. A Failure Analysis Of Two Implants, Jeremy L. Gilbert, Christine A. Buckley, Joshua J. Jacobs, Kim C. Bertin, Michael R. Zernich
Biomedical and Chemical Engineering - All Scholarship
Two modular hip implants with a cobalt-alloy head and a cobalt-alloy stem were retrieved after a fracture had occurred in the neck region of the femoral component, eighty-five and seventy months after implantation. Both implants failed less than one millimeter distal to the taper junction between the head and the stem (outside of the taper). The fracture surfaces of the implant were investigated with the use of scanning electron microscopy, to determine the nature of the failure process. The fractures occurred at the grain boundaries of the microstructure and appeared to be the result of three factors: porosity at the …
Hycrest Crested Wheatgrass Accelerates The Degradation Of Pentachlorophenol In Soil, A. Ferro, Ronald C. Sims, B. Bugbee
Hycrest Crested Wheatgrass Accelerates The Degradation Of Pentachlorophenol In Soil, A. Ferro, Ronald C. Sims, B. Bugbee
Biological Engineering Faculty Publications
We investigated the effects of vegetation on the fate of pentachlorophenol (PCP) in soil using a novel high-flow sealed test system. Pentachlorophenol has been widely used as a wood preservative, and this highly toxic biocide contaminates soil and ground water at many sites. Although plants are known to accelerate the rates of degradation of certain soil contaminants, this approach has not been thoroughly investigated for PCP. The fate of [14C]PCP, added to soil at a concentration of 100 mg/kg, was compared in three unplanted and three planted systems. The plant used was Hycrest, a perennial, drought-tolerant cultivar of crested wheatgrass …
Interposed Abdominal Compression As An Adjunct To Cardiopulmonary Resuscitation, Charles F. Babbs, Jeffrey B. Sack, Karl B. Kern
Interposed Abdominal Compression As An Adjunct To Cardiopulmonary Resuscitation, Charles F. Babbs, Jeffrey B. Sack, Karl B. Kern
Weldon School of Biomedical Engineering Faculty Publications
The addition of interposed abdominal compression (IAC) to otherwise standard CPR provides external pressure over the abdomen in counterpoint to the rhythm of chest compression. Interposed abdominal compression is a simple manual technique that can supplement the use of adrenergic drugs to increase both coronary perfusion pressure and total blood flow during CPR. Mechanistically, manual abdominal compressions induce both central aortic and central venous pressure pulses. However, owing to differences in venous versus arterial capacitance, the former are usually greater than the latter, so that systemic perfusion pressure is enhanced. Moreover, practical experience and theoretical analysis have suggested subtle refinements …
The Evolution Of Abdominal Compression In Cardiopulmonary Resuscitation, Charles F. Babbs
The Evolution Of Abdominal Compression In Cardiopulmonary Resuscitation, Charles F. Babbs
Weldon School of Biomedical Engineering Faculty Publications
Objective: To review the history of external abdominal compression as an adjunct to cardiopulmonary resuscitation (CPR), tracking the development of five major themes over the course of the 20th century: 1) augmentation of peripheral resistance by physical means, 2) risk of hepatic injury with abdominal compression, 3) counterpulsation vs. sustained compression, 4) the abdominal pump mechanism, and 5) contact compression techniques. Methods: Literature retrieved from successive MEDLINE English-language searches was reviewed with a special emphasis on work and concepts highlighted by participants at the First Purdue Conference on Interposed Abdominal Compression-CPR, September 1992. Results: External abdominal compression of one form …
Darcy-Weisbach Roughness Coefficients For Selected Crops, John E. Gilley, E. R. Kottwitz
Darcy-Weisbach Roughness Coefficients For Selected Crops, John E. Gilley, E. R. Kottwitz
Biological Systems Engineering: Papers and Publications
Total hydraulic resistance on an upland agricultural site may be influenced by several factors including standing vegetation. In this laboratory study, Darcy-Weisbach roughness coefficients were measured for corn, cotton, sorghum, soybeans, sunflower, and wheat vegetation. Experimental variables used in this investigation in addition to crop type included plant population, row spacing, row orientation, and flow rate. For some of the experimental tests, a single row of vegetation was oriented within a flume parallel to the principal flow direction. For the remainder of the tests, rows of vegetation were placed perpendicular to the flow using row spacings and plant populations recommended …
Water Vapor Permeability And Mechanical Properties Of Grain Protein-Based Films As Effected By Mixtures Of Polyethylene Glycol Amd Glycerin Plasticizers, H. J. Park, J. M. Bunn, Curtis L. Weller, P. J. Vergano, R. F. Testin
Water Vapor Permeability And Mechanical Properties Of Grain Protein-Based Films As Effected By Mixtures Of Polyethylene Glycol Amd Glycerin Plasticizers, H. J. Park, J. M. Bunn, Curtis L. Weller, P. J. Vergano, R. F. Testin
Biological Systems Engineering: Papers and Publications
Grain protein-based films containing mixtures of glycerin and polyethylene glycol (PEG) as plasticizers were prepared and evaluated for water vapor permeability (WVP), tensile strength (TS), and elongation (E). Changes in mechanical properties during storage were also studied. The PEG produced opposite trends in E of wheat gluten and corn-zein films. The TS of wheat gluten films increased and E of the films decreased as the ratio of glycerin/PEG decreased. Corn-zein films containing only glycerin were very brittle (E of 4%), and E of the films improved to 94% when the ratio of mL PEG/g protein was 0.39. The WVP of …
Long Term Tillage Effects On Grain Yield And Soil Properties In A Soybean/Grain Sorghum Rotation, Elbert C. Dickey, Paul J. Jasa, Robert Grisso
Long Term Tillage Effects On Grain Yield And Soil Properties In A Soybean/Grain Sorghum Rotation, Elbert C. Dickey, Paul J. Jasa, Robert Grisso
Biological Systems Engineering: Papers and Publications
In Nebraska, early adopters of conservation tillage, especially those using no-till planting, had some concerns regarding planter performance, early season weed control, and possible yield reductions. Selected tillage and planting systems were used long term to evaluate effects on soybean [Glycine max (L.) Merr.] and grain sorghum [Sorghum bicolor (L.) Moench] yield, soil properties, and residue cover in a non-irrigated rotation. The six tillage and planting systems selected for evaluation were: no-till, no-till with row-crop cultivation, disk, double disk, chisel, and plow. In 1981, two sets of field plots were established near Lincoln, NE, on a Sharpsburg silty …
Tillage And Planting System, Stalk Chopper, And Knife Applicator Influences On Corn Residue Cover, David P. Shelton, Stephen D. Kachman, Elbert C. Dickey, K.T. Fairbanks, Paul J. Jasa
Tillage And Planting System, Stalk Chopper, And Knife Applicator Influences On Corn Residue Cover, David P. Shelton, Stephen D. Kachman, Elbert C. Dickey, K.T. Fairbanks, Paul J. Jasa
Biological Systems Engineering: Papers and Publications
Percent corn (Zea mays L.) residue cover remaining on the soil surface after planting was measured for 11 tillage and planting systems that included combinations of the use, and timing, of a stalk chopper and/or a knife-type fertilizer applicator. Tillage, as well as use of a stalk chopper or knife applicator, significantly reduced residue cover. Only 27 of the 69 stalk chopper/knife applicator/tillage and planting system treatment combinations that were evaluated could be classified as conservation tillage by having at least 30% residue cover remaining after planting.
Moisture Adsorption By Grain Protein Films, A. Gennadios, Curtis L. Weller
Moisture Adsorption By Grain Protein Films, A. Gennadios, Curtis L. Weller
Biological Systems Engineering: Papers and Publications
Grain protein films plasticized with glycerol were prepared from corn zein (CZ), wheat gluten (WG), and a 2.3:1 mixture of wheat gluten and soy protein isolate (WG/SPI). Moisture adsorption curves of the three types of protein films at 25° C and within an approximate water activity range of 0.11 to 0.84 were obtained using a static gravimetric method. The Smith, Oswin, Halsey, and Guggenheim-Anderson-de Boer (GAB) models were applied to collected data. For all protein films, the GAB model showed the best fit over the entire studied water activity range yielding mean deviation modulus values (P) of 4.69, 3.44, and …