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Full-Text Articles in Engineering
Clinical Applications Of Recombinant Gene Technology: Bone And Cartilage Repair, Thomas A. Einhorn
Clinical Applications Of Recombinant Gene Technology: Bone And Cartilage Repair, Thomas A. Einhorn
Cells and Materials
Over the past decade, the field of molecular biology has given rise to the development of the applied discipline of molecular medicine. Based on recent developments using recombinant gene technology, genetic mapping analysis and other investigational tools, the physician and surgeon is now ready to begin using those instruments in the diagnosis and treatment of musculoskeletal disease. This article reviews the history of scientific exploration in recombinant gene technology as it applies to bone and cartilage repair. Clinical cases are presented to show how the fruits of scientific knowledge may be brought to bear on some of the more challenging …
Bone Regeneration Materials For The Mandibular And Craniofacial Complex, Jeffrey Hollinger, Anshumali Chaudhari
Bone Regeneration Materials For The Mandibular And Craniofacial Complex, Jeffrey Hollinger, Anshumali Chaudhari
Cells and Materials
Due to different functional demands and vascularity, the mandibular and craniofacial complex require bone regenerating materials with physical and chemical properties that are different from long bone. However, certain common requirements to both locales must be addressed. Furthermore, reasons why the autograft and allogeneic bank bones are successful in regenerating bone need to be understood if the researcher is to develop satisfactory alternatives. The purpose of this paper is to review some of the requirements needed for bone regenerating materials for mandibular and craniofacial bone repair. In that effort, we have briefly described the autograft and allogeneic bank bones, animal …