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Full-Text Articles in Engineering
Modification Of Lipid Microenvironments On Solid Support Structures For Use In Transmembrane Protein Assays, William J. Houlihan
Modification Of Lipid Microenvironments On Solid Support Structures For Use In Transmembrane Protein Assays, William J. Houlihan
Dissertations and Theses
Gamma-Secretase (γ-secretase) is a transmembrane protease of increasing interest, which has been shown to have significant connections to both cancer and Alzheimer’s disease. γ-secretase cleaves both Notch-1, a transmembrane signaling protein, and Amyloid precursor protein (APP), a transmembrane protein whose cleavage may result in the formation of β-amyloid plaques in the brain. Notch-1 and APP are widely studied proteins that have substantial impacts on the development and proliferation of cancer and Alzheimer’s disease, respectively. Notch-1 partakes in the signaling of apoptosis in damaged and mutated cells, thus its cleavage by γ-secretase within the plasma membrane has ramifications on cell growth …
Bio-Nano Interfaces: Enzyme Immobilization For Biomimetic Energy Harvesting, Rachel Hjelm
Bio-Nano Interfaces: Enzyme Immobilization For Biomimetic Energy Harvesting, Rachel Hjelm
Nanoscience and Microsystems ETDs
In the face of todays rapidly growing energy demands accompanied by limited, non-renewable supplies, development of novel energy alternatives that are both renewable and inexpensive has become more important than ever. Development of 3D structures exploring the properties of nano-materials and biological molecules has been shown through the years as an effective path forward for the design of advanced bio-nano architectures for enzymatic fuel cells (EFCs). Despite advantages over conventional fuel cells, EFCs still suffer from several problems including low efficiency and stability. Overcoming these limitations in order to make them more viable for real world application is an ongoing …
An Electromagnetically-Controlled Precision Orbital Tracking Vehicle (Potv), Richard E. Lawrence Jr.
An Electromagnetically-Controlled Precision Orbital Tracking Vehicle (Potv), Richard E. Lawrence Jr.
Theses and Dissertations
A propulsion configuration it defined for a precision orbital tracking vehicle (POTV) that employs electrodynamic forces to control vehicle attitude and position with respect to another spacecraft. A pair of electrically powered thrusters assist the POTV in position control. The vehicle can maintain continuous standoff at close range from another spacecraft in any direction, has docking capability, and has gross orbital transfer capability. These capabilities and the specific design derived for the POTV have been defined by the requirements of a postulated space facility (ASSET) that salvages structural aluminum from the external fuel tank of the space shuttle. Precision control …
Propulsive Capability Of A Reel-In Tether With Safe Separation Between Payload And Orbiter, Jay H. Rothhaupt
Propulsive Capability Of A Reel-In Tether With Safe Separation Between Payload And Orbiter, Jay H. Rothhaupt
Theses and Dissertations
This study investigates the use of a massless reel-in tether for propulsion of a payload following deployment from an orbiter. The distance between the payload and orbiter at closest passage is addressed. A literature review revealed several tether concepts, extensive tether research, and numerous mathematical models. However, previous work in the area of reel-in tethers is limited to propulsion feasibility. The reel-in tether is operated following optimum ejection of the payload from the orbiter using a free arc and subsequent full arc. The free arc of zero tether tension provides initial separation. Switching to a full arc of continuously-maximum tension …