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Full-Text Articles in Engineering

Experimental And Computational Tools For Single Cell Analysis In Cancer Diagnostics, Manibarathi Vaithiyanathan Jan 2020

Experimental And Computational Tools For Single Cell Analysis In Cancer Diagnostics, Manibarathi Vaithiyanathan

LSU Doctoral Dissertations

Substantial evidence shows that cellular heterogeneity commonly exists within an isogenic or clonal population. Whether in isolation or caused through a combination of the above events, cellular heterogeneity can dramatically influence cellular decision making and cell fate, however, this can be masked by the average response from a population. One approach to solve this issue is to analyze a population at the individual cell level. The goal of this work is to develop high-throughput experimental and computational platforms to screen and quantify single cancer cells for specific intracellular enzyme activities. An interdisciplinary approach was taken to 1) better understand the …


Automatic Shoreline Digitization And Mesh Element Sizing For Hydrodynamic Modeling, Henok Kefelegn Jan 2020

Automatic Shoreline Digitization And Mesh Element Sizing For Hydrodynamic Modeling, Henok Kefelegn

LSU Doctoral Dissertations

The first and most critical step in any coastal hydrodynamics and transport process modeling is identifying land-water boundaries. In a coastal wetland, this has always been a challenge due to the complexity of the wetland and lack of efficient methods, calling for efficient and effective methods to extract and digitize the shorelines. While coastline feature extraction has been increasingly researched, its application in hydrodynamic and environmental modeling, without morphological adjustment, remains limited and suboptimal. Further, there has been a paucity of cost-effective, contextually adaptive and high-quality methods to generate meshes, especially for coastal hydrodynamic modeling. This study has developed and …


Digital Image-Based Frameworks For Monitoring And Controlling Of Particulate Systems, Bing Zhang Jan 2013

Digital Image-Based Frameworks For Monitoring And Controlling Of Particulate Systems, Bing Zhang

LSU Doctoral Dissertations

Particulate processes have been widely involved in various industries and most products in the chemical industry today are manufactured as particulates. Previous research and practise illustrate that the final product quality can be influenced by particle properties such as size and shape which are related to operating conditions. Online characterization of these particles is an important step for maintaining desired product quality in particulate processes. Image-based characterization method for the purpose of monitoring and control particulate processes is very promising and attractive. The development of a digital image-based framework, in the context of this research, can be envisioned in two …


Automated Semantic Content Extraction From Images, Mahdi Arab Khazaeli Jan 2013

Automated Semantic Content Extraction From Images, Mahdi Arab Khazaeli

LSU Doctoral Dissertations

In this study, an automatic semantic segmentation and object recognition methodology is implemented which bridges the semantic gap between low level features of image content and high level conceptual meaning. Semantically understanding an image is essential in modeling autonomous robots, targeting customers in marketing or reverse engineering of building information modeling in the construction industry. To achieve an understanding of a room from a single image we proposed a new object recognition framework which has four major components: segmentation, scene detection, conceptual cueing and object recognition. The new segmentation methodology developed in this research extends Felzenswalb's cost function to include …