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Theses/Dissertations

Image processing

University of Iowa

Articles 1 - 4 of 4

Full-Text Articles in Engineering

Differentiation Between Causes Of Optic Disc Swelling Using Retinal Layer Shape Features, John William Miller May 2018

Differentiation Between Causes Of Optic Disc Swelling Using Retinal Layer Shape Features, John William Miller

Theses and Dissertations

The optic disc is the region of the retina where the optic nerve exits the back of the eye. A number of conditions can cause the optic disc to swell. Papilledema, optic disc swelling caused by raised intracranial pressure (ICP), and nonarteritic anterior ischemic optic neuropathy (NAION), swelling caused by reduced blood flow to the back of the eye, are two such conditions. Rapid, accurate diagnosis of the cause of disc swelling is important, as with papilledema the underlying cause of raised ICP could potentially be life-threatening and may require immediate intervention.

The current clinical standard for diagnosing and assessing ...


Automated Segmentation And Analysis Of Layers And Structures Of Human Posterior Eye, Li Zhang Dec 2015

Automated Segmentation And Analysis Of Layers And Structures Of Human Posterior Eye, Li Zhang

Theses and Dissertations

Optical coherence tomography (OCT) is becoming an increasingly important modality for the diagnosis and management of a variety of eye diseases, such as age-related macular degeneration (AMD), glaucoma, and diabetic macular edema (DME). Spectral domain OCT (SD-OCT), an advanced type of OCT, produces three dimensional high-resolution cross-sectional images and demonstrates delicate structure of the functional portion of posterior eye, including retina, choroid, and optic nerve head. As the clinical importance of OCT for retinal disease management and the need for quantitative and objective disease biomarkers grows, fully automated three-dimensional analysis of the retina has become desirable. Previously, our group has ...


Automated Delineation And Quantitative Analysis Of Blood Vessels In Retinal Fundus Image, Xiayu Xu May 2012

Automated Delineation And Quantitative Analysis Of Blood Vessels In Retinal Fundus Image, Xiayu Xu

Theses and Dissertations

Automated fundus image analysis plays an important role in the computer aided diagnosis of ophthalmologic disorders. A lot of eye disorders, as well as cardiovascular disorders, are known to be related with retinal vasculature changes. Many studies has been done to explore these relationships. However, most of the studies are based on limited data obtained using manual or semi-automated methods due to the lack of automated techniques in the measurement and analysis of retinal vasculature. In this thesis, a fully automated retinal vessel width measurement technique is proposed. This novel method models the accurate vessel boundary delineation problem in two-dimension ...


Novel Computer Vision Algorithms For Automated Cell Event Detection And Analysis, In Ae Hur May 2012

Novel Computer Vision Algorithms For Automated Cell Event Detection And Analysis, In Ae Hur

Theses and Dissertations

Live cell imaging is the study of living cells using microscope images and is used by biomedical researchers to provide a novel way to analyze biological functions through cell behavior and motion studies. Cell events are seen as morphological changes in image sequences, and their analysis has great potential for the study of normal/abnormal phenotypes and the effectiveness of drugs. While current quantitative cell analysis typically focuses on measuring whole populations of cells, we need to be able to recognize cell events at the single cell level, identify these events automatically, and analyze these events over time. For this ...