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Full-Text Articles in Engineering

Synthesis Of Monodisperse Nanoscintillators At High Temperatures For Biomedical Relevant Applications, Eric Zhang May 2022

Synthesis Of Monodisperse Nanoscintillators At High Temperatures For Biomedical Relevant Applications, Eric Zhang

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Luminescent sub-100 nm particulates continuously generate immense research interest in the biomedical field for imaging, theranostics, and optogenetics. Conventionally, upconversion nanoparticles or UV activated semiconductors are studied, however these materials are limited by biological barriers such as the skin which reduces the penetration depth of these excitation sources, tissue's auto- fluorescence, and toxicity. One approach to overcome these challenges is to use nanoscintillators (sub-100 nm materials that can generate visible light using high energy excitation sources such as x-rays) which can generate light locally to the human body. Numerous scintillators have been reported since the discovery of x-rays from the …


Methods Development And Force Field Evaluation For Molecular Simulations Of Interactions Between Structured Peptides And Functionalized Material Surfaces, Galen Collier May 2011

Methods Development And Force Field Evaluation For Molecular Simulations Of Interactions Between Structured Peptides And Functionalized Material Surfaces, Galen Collier

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The process of protein adsorption to material surfaces is highly complex and it is one of the most fundamental concepts upon which progress in the field of bioengineering is based. The strategic design of material surfaces for optimal utility in specific biological environments is absolutely dependent upon a thorough understanding of the mechanisms underlying protein adsorption, yet there is still a very limited understanding of these mechanisms. The primary reason for this lack of understanding is that protein adsorption is a dynamic process which occurs at the atomic and macromolecular scale, where experimental analyses provide a view that is static …