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Multichannel Characterization Of Brain Activity In Neurological Impairments, Yalda Shahriari
Multichannel Characterization Of Brain Activity In Neurological Impairments, Yalda Shahriari
Biomedical Engineering Theses & Dissertations
Hundreds of millions of people worldwide suffer from various neurological and psychiatric disorders. A better understanding of the underlying neurophysiology and mechanisms for these disorders can lead to improved diagnostic techniques and treatments. The objective of this dissertation is to create a novel characterization of multichannel EEG activity for selected neurological and psychiatric disorders based on available datasets. Specifically, this work provides spatial, spectral, and temporal characterizations of brain activity differences between patients/animal models and healthy controls, with focus on modern techniques that quantify cortical connectivity, which is widely believed to be abnormal in such disorders. Exploring the functional brain …
Assessment Of Antipsychotic Medication Effects On Dynamic Functional Network Connectivity In Patients With Schizophrenia, Kristin Lottman
Assessment Of Antipsychotic Medication Effects On Dynamic Functional Network Connectivity In Patients With Schizophrenia, Kristin Lottman
All ETDs from UAB
Schizophrenia, a psychiatric disorder affecting approximately 1% of the population, is often characterized as a disorder of dysconnectivity. Evaluation of the dysconnectivity hypothesis of schizophrenia has been extensively examined via functional neuroimaging studies in order to enhance insight into the disorder’s pathology. In particular, resting-state functional connectivity analyses have reported widespread aberrant network connectivity between brain regions in patients; however, consistencies in the directionality of abnormalities are often variable across studies. Recent investigations have begun to analyze functional connectivity dynamically as it is likely these inconsistencies may be a result of the static nature of traditional connectivity measures. In this …