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Theses/Dissertations

2014

Electronic Theses and Dissertations

University of Louisville

Autism--Diagnosis

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Full-Text Articles in Engineering

Fast And Robust Hybrid Framework For Infant Brain Classification From Structural Mri : A Case Study For Early Diagnosis Of Autism., Amir Alansary Aug 2014

Fast And Robust Hybrid Framework For Infant Brain Classification From Structural Mri : A Case Study For Early Diagnosis Of Autism., Amir Alansary

Electronic Theses and Dissertations

The ultimate goal of this work is to develop a computer-aided diagnosis (CAD) system for early autism diagnosis from infant structural magnetic resonance imaging (MRI). The vital step to achieve this goal is to get accurate segmentation of the different brain structures: whitematter, graymatter, and cerebrospinal fluid, which will be the main focus of this thesis. The proposed brain classification approach consists of two major steps. First, the brain is extracted based on the integration of a stochastic model that serves to learn the visual appearance of the brain texture, and a geometric model that preserves the brain geometry during …


A Novel Diffusion Tensor Imaging-Based Computer-Aided Diagnostic System For Early Diagnosis Of Autism., Mahmoud Mostapha Aug 2014

A Novel Diffusion Tensor Imaging-Based Computer-Aided Diagnostic System For Early Diagnosis Of Autism., Mahmoud Mostapha

Electronic Theses and Dissertations

Autism spectrum disorders (ASDs) denote a significant growing public health concern. Currently, one in 68 children has been diagnosed with ASDs in the United States, and most children are diagnosed after the age of four, despite the fact that ASDs can be identified as early as age two. The ultimate goal of this thesis is to develop a computer-aided diagnosis (CAD) system for the accurate and early diagnosis of ASDs using diffusion tensor imaging (DTI). This CAD system consists of three main steps. First, the brain tissues are segmented based on three image descriptors: a visual appearance model that has …