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Silicone hydrogel; Polyethylene glycol (PEG); Polyvinylpyrrolidone (PVP); Silver nanoparticles; Zinc oxide nanoparticles; Surface coating; Matrix assisted pulsed laser evaporation (MAPLE); protein adsorption; Antibacterial property.
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Laser-Assisted Surface Modification Of Hybrid Hydrogels To Prevent Bacterial Contamination And Protein Fouling, Guobang Huang
Laser-Assisted Surface Modification Of Hybrid Hydrogels To Prevent Bacterial Contamination And Protein Fouling, Guobang Huang
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Silicone hydrogels have been extensively studied in the fields of contact lenses, tissue engineering, and drug delivery due to their good biocompatibility, high oxygen permeability, and proper light transmission. However, their applications in biomedical devices are limited by protein adsorption and bacterial contamination because of the hydrophobic surface of silicone, which will cause more irreversible protein adsorption. Several physical methods can be applied to create a hydrophilic surface on hydrogels, such as spin coating, physical vapor deposition, dip coating, drop casting, etc. Compared to the conventional methods, the matrix assisted pulsed laser evaporation (MAPLE) is suitable to produce biopolymer/polymer film …