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Electrostatically Controlled Enzymatic Reaction, Metabolic Processes And Microbial Generation Of Electric Power, Yang Song

ETD Archive

This thesis shows that electric fields can be used to control electron transport in biological systems and improve the performance of biological devices using an external gating voltage. It has recently been shown that an ultrasensitive detection method based on electric field effect can be used to control the kinetics of enzymatic conversion of glucose. The first part of the thesis is a mechanistic study of the enzyme catalyzed conversion of glucose to gluconolactone using the field effect enzymatic detection (FEED) technique. Use of a voltage controlled enzymatic system decreased electrons tunnel between electrode and active center of glucose oxidase …